14512-85-7

Basic information

• Product Name: 4-AMINO-3-FLUOROPHENYL THIOCYANATE
• Synonyms: 2-Fluoro-4-thiocyanatoaniline;Thiocyanic acid,4-aMino-3-fluorophenyl ester
• CAS NO: 14512-85-7
• Molecular Formula: C₇H₅FN₂S
• Molecular Weight: 168.19
• Mol File: 14512-85-7.mol
• Article Data: 12

Chemical Properties

• Boiling Point: 285.2°Cat760mmHg
• Flash Point: 126.3°C
• Appearance: /
• Density: 1.37g/cm³
• Vapor Pressure: 0.00284mmHg at 25°C
• Refractive Index: 1.62
• CAS DataBase Reference: 4-AMINO-3-FLUOROPHENYL THIOCYANATE(CAS DataBase Reference)
• NIST Chemistry Reference: 4-AMINO-3-FLUOROPHENYL THIOCYANATE(14512-85-7)
• EPA Substance Registry System: 4-AMINO-3-FLUOROPHENYL THIOCYANATE(14512-85-7)

Safety Data

• Hazardous Substances Data: 14512-85-7(Hazardous Substances Data)

Usage

General Description

4-AMINO-3-FLUOROPHENYL THIOCYANATE is a chemical compound with the molecular formula C7H5FN2S. It is a thiocyanate derivative with a fluorine atom and an amino group attached to a phenyl ring. 4-AMINO-3-FLUOROPHENYL THIOCYANATE is commonly used in the pharmaceutical industry for the synthesis of various drugs and biologically active compounds. It has potential applications in medicinal chemistry and drug discovery research. The compound is known for its ability to act as a building block in the preparation of complex organic molecules and has shown promising pharmacological properties in preliminary studies. Additionally, it has been studied for its potential as an antifungal agent and may have applications in the agricultural industry as well.

InChI:InChI=1/C7H5FN2S/c8-6-3-5(11-4-9)1-2-7(6)10/h1-3H,10H2

Upstream product

• 348-54-9 2-Fluoroaniline 
• 333-20-0 potassium thioacyanate 
• 1147550-11-5 ammonium thiocyanate 
• 540-72-7 sodium thiocyanide 

Downstream Products

• 76180-33-1 [2-fluoro-4-(methylthio)phenyl]amine 
• 75867-50-4 2-fluoro-4-ethylthioaniline 
• 1378859-72-3 C₆H₅FNS^(1-)*Na⁽¹⁺⁾ 

Relevant articles and documents

Method for inducing thiocyanation of arylamine compound by visible light

The invention discloses a method for inducing thiocyanation of an arylamine compound by visible light. Specifically, in the atmosphere of oxygen or air, an arylamine compound, an ammonium thiocyanatecompound and copper chloride dihydrate are added into a

Copper-Catalyzed Aerobic Oxidative Regioselective Thiocyanation of Aromatics and Heteroaromatics

A copper-catalyzed aerobic oxidative reaction between aromatics or heteroaromatics with KSCN is developed by using O2 as the oxidant. The combination of Cu(OTf)2, N,N,N′,N′-tetramethylethylenediamine (TMEDA) and BF3·Et2O provides an efficient catalytic system, affording substituted thiocyanation products and 2-aminobenzothiazoles in excellent yields. The reaction also possesses a good functional group tolerance for both strong electron-withdrawing and electron-donating groups.

4-(TRICHLOROMETHYLTHIO)ANILINE, METHOD FOR PRODUCING THE SAME, AND METHOD FOR PRODUCING 4-(TRIFLUOROMETHYLTHIO)ANILINE

There are provided a 4-(trichloromethylthio)aniline represented by the general formula (II): wherein R1 represents a hydrogen atom or an alkyl group having 1 to 3 carbon atoms, R2 each independently represents a halogen atom, an alkyl group having 1 to 3 carbon atoms, or a perfluoroalkyl group having 1 to 3 carbon atoms, R3 represents a formyl group, an acetyl group, or a trifluoroacetyl group, and m represents an integer of 0 to 4, a method for producing the same, and a method for producing a 4-(trifluoromethylthio)aniline derivative using the 4-(trichloromethylthio)aniline. It becomes possible to produce a 4-(trifluoromethylthio)aniline with a high yield by using raw materials that can easily be obtained industrially and using general purpose production facilities.