145143-89-1Relevant academic research and scientific papers
Mesoporous MFI Zeolite with a 2D Square Structure Directed by Surfactants with an Azobenzene Tail Group
Shen, Xuefeng,Mao, Wenting,Ma, Yanhang,Peng, Honggen,Xu, Dongdong,Wu, Peng,Han, Lu,Che, Shunai
, p. 8615 - 8623 (2018)
Mesoporous MFI zeolites (MMZs) have been constructed by using the surfactant-containing azobenzene segment in the hydrophobic tail. The cylindrical π–π stacking of azeobenzene groups is considered to be the key factor to form the ordered mesostructure thr
End-Group-Dominated Molecular Order in Self-Assembled Monolayers
Wolf H.,Ringsdorf, H.,Delemarche, E.,Takami, T.,Kang, H.,et al.
, p. 7102 - 7107 (1995)
Self-assembled monolayers of 6-hexane-1-thiol ("azobenzene") on gold have been studied with atomic force microscopy in ethanol and with scanning tunneling microscopy at high gap impedance in air.These azobenzene-functionalized self-a
The structure of [4-(phenylazo)phenoxy]hexane-1-thiol self-assembled monolayers on Au(111)
Mannsfeld,Canzler,Fritz,Proehl,Leo,Stumpf,Goretzki,Gloe
, p. 2255 - 2260 (2002)
The structure of [4-(phenylazo)phenoxy]hexane-1-thiol (AzoC6) self-assembled monolayers (SAMs) on Au(111) has been investigated with scanning tunneling microscopy (STM) and Fourier transform infrared-reflection absorption spectroscopy (FTIR-RAS). The FTIR-RAS results yield a tilt angle of the molecules close to 0?°, which significantly differs from the 30?° tilt angle of linear n-alkanethiols. In STM images two types of domains are observed that have equal unit cell dimensions and two molecules per unit cell but show different tunneling contrasts, which is attributed to a different arrangement of the molecules within the unit cell. The relationship of the molecular lattice to the substrate lattice is found to be commensurate.
New photochromic azoderivatives with potent acetylcholinesterase inhibition
Arroyo Ma?ez, Pau,Biscussi, Brunella,Murray, Ana Paula,Richmond, Victoria,Sequeira, Maria Alejandra
, (2021/06/12)
The design of photochromic cholinesterase inhibitors is a challenge of the photopharmacological approach towards the remote control of acetylcholinesterase (AChE) enzyme and its potential application in Alzheimer's disease therapy. In this work, a series of azoderivatives were designed, synthesized and evaluated as AChE inhibitors. The optimized microwave-assisted synthesis (two steps) showed excellent yields with a total reaction time no longer than 40 min. The results showed that all the synthesized compounds exhibited high AChE inhibitory activity at the micromolar range (IC50, 0.65–8.52 μM). Moreover, compound 19, with double four-hydrocarbon chain connected to piperidine, showed a powerful in vitro enzymatic response for its Z isomer (IC50: 0.43 μM) determined by Ellman's assay. Also, 19 showed a stable photostationary state monitored by UV/Vis absorption spectroscopy and 1H NMR spectra. These results indicate that 19 can act as an efficient photo-responsible probe to remote control AChE activity. Molecular modelling analysis of 19 Z revealed its affinity by the peripheral anionic site of AChE, providing understanding of its higher inhibition power. This study contributes to the development of new promising agents for photopharmacological treatment of Alzheimer's disease.
Photo-isomerization and light-modulated aggregation behavior of azobenzene-based ionic liquids in aqueous solutions
Li, Zhiyong,Wang, Huiyong,Chu, Mengen,Guan, Pengxin,Zhao, Yang,Zhao, Yuling,Wang, Jianji
, p. 44688 - 44695 (2017/10/13)
Light modulation of the isomerization and aggregation behavior of ionic liquids in aqueous solution is of great importance from a fundamental and technical point of view. In this work, 4 kinds of azobenzene-based photoresponsive ionic liquids 2-hydroxyeth
Functional poly(phenylacetylene)s carrying azobenzene pendants: Polymer synthesis, photoisomerization behaviors, and liquid-crystalline property
Xiao, A.-Zhang,Zhao, Hui,Gao, Yuan,Tong, Jiaqi,Shan, Liang,Chen, Yufei,Zhang, Shuang,Qin, Anjun,Sun, Jing Zhi,Tang, Ben Zhong
, p. 5290 - 5301 (2012/06/04)
Functional poly(phenylacetylene)s (PPAs) bearing different azobenzene pendants were synthesized in desirable yields and molecular weight by using organorhodium complexes [Rh(diene)Cl]2 as catalysts. The structure of the derived azobenzene-functionalized PPAs was characterized by NMR, IR, and UV spectroscopic techniques. Their photoinduced isomerization behavior was monitored with UV-visible spectroscopy. The thermal stability was evaluated by TGA technique. Polarized optical microscope (POM) observations indicated that the PPAs constructed by linking azobenzene moieties via a longer flexible alkyl spacer to PPA backbone showed typical liquid-crystalline property and the mesophase was assigned to SmA phase. Their phase transition behaviors were further investigated by differential scanning calorimetric (DSC) measurements. The molecular packing modes were analyzed by using X-ray diffraction (XRD) measurement and theoretical simulation. These results revealed some details about the interactions between the polymer backbone, flexible alkyl spacer, and azobenzene functional moiety, which are constructive to design and synthesize novel functional conjugated polymers.
