14527-42-5

Usage

Uses

Used in Flavor and Fragrance Industry:
Ethyl thiazole-2-carboxylate is used as a flavoring agent and fragrance ingredient for its ability to impart a nutty, roasted, and meaty aroma to products. This makes it a valuable addition in the formulation of food, beverages, and cosmetics, enhancing the sensory experience of these consumer products.
Used in Food Industry:
In the food industry, Ethyl thiazole-2-carboxylate is used as a flavor enhancer to give a rich, meaty taste to various products such as meat, baked goods, and savory snacks, thereby improving their overall flavor profile.
Used in Beverage Industry:
Ethyl thiazole-2-carboxylate is utilized in the beverage industry to add depth and complexity to the taste of drinks, particularly those that aim to mimic or complement the flavors found in certain types of food.
Used in Cosmetic Industry:
In cosmetics, Ethyl thiazole-2-carboxylate serves as a fragrance ingredient, contributing to the scent of products and providing a pleasant olfactory experience for the user.
Used in Pharmaceutical Industry:
Ethyl thiazole-2-carboxylate is also used in the production of pharmaceuticals, where its unique properties may contribute to the development of new drugs or improve the delivery and effectiveness of existing medications.
Used in Agricultural Chemicals Industry:
Furthermore, Ethyl thiazole-2-carboxylate finds application in the agricultural chemicals sector, potentially enhancing the efficacy of agrochemical products or contributing to the development of novel formulations for crop protection and enhancement.

Upstream product

• 79265-30-8 2-(trimethylsilyl)thiazole 
• 541-41-3 chloroformic acid ethyl ester 
• 107-20-0 2-chloroethanal 
• 16982-21-1 ethyl 2-amino-2-thioxoacetate 
• 108-24-7 acetic anhydride 

Downstream Products

• 53101-04-5 ethyl 4-(4-nitrophenyl)-1,3-thiazole-2-carboxylate 
• 630422-15-0 N,N-diethyl-4-methoxy-2-(2-oxo-2-thiazol-2-yl-ethyl)-benzamide 
• 1006044-74-1 N-(1-methyl-1-phenylethyl)thiazole-2-carboxamide 
• 14542-12-2 (1,3-thiazol-2-yl)methanol 
• 16733-90-7 1,3-thiazole-2-carbohydrazide 
• 14190-59-1 1,3-thiazole-2-carboxylic acid 
• 16733-85-0 thiazole-2-carboxamide 
• 24295-03-2 2-Acetylthiazole 

Relevant academic research and scientific papers

REACTIONS OF 2-TRIMETHYLSILYLYHIAZOLE WITH ACYL CHLORIDES AND ALDEHYDES SYNTHESIS OF NEW THIAZOL-2-YL DERIVATES

2-Trimethylsilylthiazole (1) undergoes ipso-substitution of the silyl group with various acyl chlorides and ethyl chloroformate affording 2-acylthiazoles (2)-(5) but adds by the carbon-silicon bond to the carbonyl group of aldehydes yielding thiazol-2-yl-trimethylsiloxy-methane derivates (7).

Substituted pyrrole chromone compound or pharmaceutically acceptable salt thereof and preparation method and application thereof

The invention discloses a substituted pyrrole chromone compound or pharmaceutically acceptable salt thereof and a preparation method and application thereof. The structure of the compound or the pharmaceutically acceptable salt thereof is shown in the for

PYRAZOLO[4,3-D]THIAZOLE DERIVATIVES, AND PREPARATION AND THERAPEUTIC APPLICATION THEREOF

The disclosure relates to a compound of formula (I): in which: R1, R2, R3 and R4 are as described in the specification, to compositions containing them and to their therapeutic use, especially as anticancer agen

THIAZOLE PYRAZOLOPYRIMIDINES AS CRF1 RECEPTOR ANTAGONISTS

The present invention relates to compounds of Formula (I), pharmaceutical compositions thereof, and use thereof as corticotropin releasing factor 1 (CRF1) receptor antagonists in the treatment of psychiatric and neuroendocrine disorders, neurological dise

1-(Aromatic- or heteroaromatic-substituted)-3-(heteroaromatic substituted)-1,3-propanediones and uses thereof

Certain 1-(aromatic- or heteroaromatic-substituted-3-(heteroaromatic substituted)-1,3-propanediones are described as inhibitors of HIV integrase and inhibitors of HIV replication. These compounds are useful in the prevention or treatment of infection by HIV and the treatment of AIDS, either as compounds, pharmaceutically acceptable salts, pharmaceutical composition ingredients, whether or not in combination with other antivirals, immunomodulators, antibiotics or vaccines. Methods of treating AIDS and methods of preventing or treating infection by HIV are also described.

Synthesis of (Trimethylsilyl)thiazoles and Reactions with Carbonyl Compounds. Selectivity Aspects and Synthetic Utility

Synthetic routes to all possible regioisomeric mono- and bis(trimethylsilyl)thiazoles as well as to the tris(trimethylsilyl) derivative via lithiation-silylation sequences of the thiazole ring followed by selective protodesilylation in some cases are described. (Trimethylsilyl)thiazoles serve as thiazolyl donor synthons upon reaction with carbonyl compounds (ketenes, acyl chlorides, aldehydes) for the preparation of mono- and bis-substituted thiazoles in very good yields.Carbodesilylation occurs more readily at the 2- than 5-position, whereas no reaction takes place at the 4-position.A mechanism via a thiazolium 2-ylide as an intermediate is suggested for the carbodesilylation at the 2-position.

NEW PERSPECTIVES IN THIAZOLE CHEMISTRY

Carbon-carbon bond forming reactions at C-2 of the thiazole ring have been carried using two strategies, one involving the addition of organometallic reagents (lithium carbanions of esters, Grignard salts, silyl enol ethers, silyl ketene acetals, silylazoles) to N-acylthiazolium salts; the other involving the addition of carbon electrophiles (ketenes, acyl chlorides, anhydrides, aldehydes) to N-acylthiazolium ylides generated in situ.The reactions have been applied to 1,3-thiazole and 2-trimethylsilyl-1,3-thiazole, the latter being more reactive than the former toward electrophiles.This methodology constitutes a new entry to a variety of functionalized thiazoles and thiazolines which are potential building blocks for the synthesis of natural compounds and analogues of biologically active molecules (penems, arylpropionic acids).Some ring transformations of thiazoles induced by carbon-sulfur bond cleavage are also described.The fundamental role played by the sulfur atom of the thiazole ring in the observed reactions is pointed out and briefly discussed.