14527-46-9

Usage

Uses

Used in Pharmaceutical Industry:
5-NITRO-1,3-THIAZOLE 96 is used as a building block for the synthesis of various pharmaceuticals due to its unique chemical properties and reactivity, contributing to the development of new drugs and therapeutic agents.
Used in Agrochemical Industry:
In the agrochemical sector, 5-NITRO-1,3-THIAZOLE 96 is utilized as a key component in the synthesis of agrochemicals, playing a vital role in the creation of pesticides, herbicides, and other crop protection products.
Used in Dye and Pigment Manufacturing:
5-NITRO-1,3-THIAZOLE 96 is employed as a precursor in the manufacturing of dyes and pigments, providing a foundation for the production of a wide range of colorants used in various industries, including textiles, plastics, and printing inks.
Used in Organic Compound Synthesis:
As a versatile chemical intermediate, 5-NITRO-1,3-THIAZOLE 96 is used in the synthesis of various organic compounds, enabling the development of new materials and chemical products with diverse applications across different industries.

InChI:InChI=1/C3H2N2O2S/c6-5(7)3-1-4-2-8-3/h1-2H

Upstream product

• 121-66-4 2-amino-5-nitro-1,3-thiazole 
• 39920-61-1 5-nitro-2-thiazole 2-carboxylic acid 
• 3034-48-8 2-bromo-5-nitro-1,3-thiazole 

Downstream Products

• 408507-23-3 N-(thiazol-5-yl)acetamide 

Relevant academic research and scientific papers

Deamination of 2-aminothiazoles and 3-amino-1,2,4-triazines with nitric oxide in the presence of a catalytic amount of oxygen

2-Aminothiazoles, 2-aminobenzazoles, and 3-amino-1,2,4-triazines were deaminated using nitric oxide (NO) in the presence of a catalytic amount of oxygen to afford corresponding unsubstituted heterocycles in good yields.

Formation of ?-Anionic Complexes in Reactions between 5-Nitrothiazole, 6-Nitrobenzothiazole and Tetrabutylammonium Borohydride

The title reactions were performed in toluene, tetrahydrofuran (THF) and dimethylsulfoxide. 1H NMR spectral data from the reaction mixtures in Me2SO and in THF indicate that each substrate affords only one respective ?-anionic complex.Kinetic data on formation of the complexes indicate that the attack of the nuclophile and stability of the complexes are affected greatly by changing the solvent.In agreement with our previous findings, in Me2SO the rate of formation of the complexes from both substrates considered is lower than that observed in less polar solvents (toluene and THF).The explanation of this trend includes comparison of charge dispersion in the transition state with respect to the initial state and the possibility of changes in the hydride ion carrier when the solvent is changed.