1452772-89-2

Upstream product

• 1452772-87-0 1,3-dibromo-5-(3-methoxy-3-methylbut-1-yn-1-yl)benzene 
• 626-39-1 1,3,5-trisbromobenzene 
• 1452772-88-1 ((5-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-phenylene)bis(ethyne-2,1-diyl))bis(trimethylsilane) 
• 13994-57-5 3-methoxy-3-methylbut-1-yne 

Downstream Products

• 1452772-92-7 5-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-bis(1-(3,5-bis(trifluoromethyl)-phenyl)-1H-1,2,3-triazol-4-yl)benzene 
• 1452772-94-9 5-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-bis(1-perfluorophenyl-1H-1,2,3-triazol-4-yl)benzene 
• 1452772-90-5 1,3-bis(1-isopropyl-1H-1,2,3-triazol-4-yl)-5-(3-methoxy-3-methylbut-1-yn-1-yl)benzene 
• 1452772-91-6 5-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-bis(1-phenyl-1H-1,2,3-triazol-4-yl)benzene 
• 1452772-93-8 5-(3-methoxy-3-methylbut-1-yn-1-yl)-1,3-bis(4-N,N-dimethylaniline-1H-1,2,3-triazol-4-yl)benzene 

Relevant academic research and scientific papers

Chiral Triazoles in Anion-Binding Catalysis: New Entry to Enantioselective Reissert-Type Reactions

Easily accessible and tunable chiral triazoles have been introduced as a novel class of C-H bond-based H-donors for anion-binding organocatalysis. They have proven to be effective catalysts for the dearomatization reaction of different N-heteroarenes. Although this dearomatization approach represents a powerful strategy to build chiral heterocycles, to date only a few catalytic methods to this end exist. In this work, the organocatalyzed enantioselective Reissert-type dearomatization of isoquinoline derivatives employing a number of structurally diverse chiral triazoles as anion-binding catalysts was realized. The here presented method was employed to synthesize a number of chiral 1,2-dihydroisoquinoline substrates with an enantioselectivity up to 86:14 e.r. Moreover, a thorough study of the determining parameters affecting the activity of this type of anion- binding catalysts was carried out.

"Click" bis-triazoles as neutral C-H?anion-acceptor organocatalysts

A new player on the field! "Click" bis-triazoles have been introduced as a highly efficient new class of neutral C-H?anion-binding organocatalysts (see scheme). DFT and NMR studies were used to confirm this activation modus and identify the optimal catalyst. Copyright