145452-10-4

Upstream product

• 640-68-6 D-Val-OH 
• 24424-99-5 di-tert-butyl dicarbonate 
• 178676-31-8 (R)-2-[(S)-3-tert-Butoxycarbonylamino-3-methoxycarbonyl-4-phenyl-but-(E)-ylideneamino]-2-isopropyl-5-methyl-hex-4-enoic acid methyl ester 
• 147240-32-2 (2R,4R)-4-Benzyl-2-tert-butyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester 
• 145484-23-7 (R)-2-Amino-2-benzyl-5-methyl-hex-4-enoic acid methyl ester 
• 145452-09-1 (S)-2-tert-Butoxycarbonylamino-2-[(R)-5-isopropyl-5-(3-methyl-but-2-enyl)-4-oxo-4,5-dihydro-1H-pyrrol-3-yl]-3-phenyl-propionic acid methyl ester 
• 145452-07-9 (R)-2-Benzyl-2-tert-butoxycarbonylamino-5-methyl-hex-4-enoic acid methyl ester 
• 159215-97-1 (S)-2-Benzyl-2-tert-butoxycarbonylamino-4-oxo-butyric acid methyl ester 
• 147240-34-4 (2R,4R)-2-tert-Butyl-4-isopropyl-4-(3-methyl-but-2-enyl)-5-oxo-oxazolidine-3-carboxylic acid allyl ester 
• 147240-38-8 (R)-2-Allyloxycarbonylamino-2-benzyl-5-methyl-hex-4-enoic acid methyl ester 
• 147240-35-5 (R)-2-Allyloxycarbonylamino-2-benzyl-5-methyl-hex-4-enoic acid 
• 147240-29-7 (2R,4R)-4-Benzyl-2-tert-butyl-5-oxo-oxazolidine-3-carboxylic acid allyl ester 
• 147240-31-1 (2R,4R)-2-tert-Butyl-4-isopropyl-5-oxo-oxazolidine-3-carboxylic acid allyl ester 
• 147240-40-2 (R)-2-Allyloxycarbonylamino-2-isopropyl-5-methyl-hex-4-enoic acid methyl ester 

Downstream Products

• 145452-12-6 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S)-5'-isobutyl-2-isopropyl-5'-(3-methyl-but-2-enyl)-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 
• 145452-06-8 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S,5''S)-5',5''-diisobutyl-2-isopropyl-5''-(3-methyl-but-2-enyl)-3,4',4''-trioxo-2,3,4',5',4'',5''-hexahydro-1H,1'H,1''H-[2,3';5',3'']terpyrrol-4-yl]-3-phenyl-propionic acid methyl ester 
• 288404-56-8 2-tert-butoxycarbonylamino-2-[5''-(2-hydroxy-ethyl)-5',5''-diisobutyl-2-isopropyl-3,4',4''-trioxo-2,3,4',5',4'',5''-hexahydro-1H,1'H,1''H-[2,3';5',3'']terpyrrol-4-yl]-3-phenyl-propionic acid methyl ester 
• 288404-55-7 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S)-5'-(2-hydroxy-ethyl)-5'-isobutyl-2-isopropyl-3,4'-dioxo-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 
• 159216-07-6 CHCH₂CCOCH₂C₆H₅NCO₂C₄H₉NCC₃H₇COCCHNHCC₄H₉CH₂COHCONCC₄H₉COCH₂CNCCH₂C₆H₅COCH₃CH₂CHC₃H₅ 
• 159216-06-5 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S,5''S)-5',5''-diisobutyl-2-isopropyl-3,4',4''-trioxo-5''-(2-oxo-ethyl)-2,3,4',5',4'',5''-hexahydro-1H,1'H,1''H-[2,3';5',3'']terpyrrol-4-yl]-3-phenyl-propionic acid methyl ester 
• 145452-13-7 (S)-2-tert-Butoxycarbonylamino-2-[(2S,5'S)-5'-isobutyl-2-isopropyl-3,4'-dioxo-5'-(2-oxo-ethyl)-2,3,4',5'-tetrahydro-1H,1'H-[2,3']bipyrrolyl-4-yl]-3-phenyl-propionic acid methyl ester 

Relevant academic research and scientific papers

A second-generation synthesis of polypyrrolinone nonpeptidomimetics: prelude to the synthesis of polypyrrolinones on solid support.

[reaction: see text] A second-generation asymmetric synthesis of polypyrrolinones (3) has been achieved exploiting scalemic alpha-aminolactones (1) as building blocks. Imine formation between an appropriate lactone (1) and aldehyde (2), followed in turn b

De novo design, synthesis, and X-ray crystal structures of pyrrolinone-based β-strand peptidomimetics

The de novo design and synthesis of a novel non-peptide scaffolding for β-strand/sheet mimics are described. The scaffold consists of repeating 3,5,5-trisubstituted pyrrolinone (enaminone) units punctuated with appropriate amino acid side chains. The iter