145472-47-5

Basic information

• Product Name: (2S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile
• Synonyms: (2S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile
• CAS NO: 145472-47-5
• Molecular Weight: 518.752
• Mol File: 145472-47-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile(145472-47-5)
• EPA Substance Registry System: (2S,5S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbonitrile(145472-47-5)

Safety Data

• Hazardous Substances Data: 145472-47-5(Hazardous Substances Data)

Upstream product

• 132974-84-6 (-)-(5S)-5-{[(tert-butyldiphenylsilyl)oxy]methyl}-1-tosylpyrrolidin-2-one 
• 7677-24-9 trimethylsilyl cyanide 
• 143264-72-6 N-p-toluenesulphonyl(5-diphenyl-tert-butylsilyloxymethyl)-2-hydroxypyrrolidine 

Downstream Products

• 145472-49-7 [(S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-methanol 
• 92198-73-7 [(S)-5-Hydroxymethyl-1-(toluene-4-sulfonyl)-pyrrolidin-2-yl]-methanol 
• 145472-48-6 (S)-5-(tert-Butyl-diphenyl-silanyloxymethyl)-1-(toluene-4-sulfonyl)-pyrrolidine-2-carbaldehyde 

Relevant articles and documents

Carbon-Carbon Bond Formation via N-Tosyliminium Ions

Addition of carbon nucleophiles to cyclic N-tosyliminium ions, derived from α-hydroxy and α-methoxy tosylamides (5a,b and 6a,b, respectively) is described.In general, good to excellent yields were obtained when allyltrimethylsilane, 1-t-butyldimethylsilyl