1454769-81-3

Basic information

• Product Name: N-(2-iodophenyl)-2-phenylacrylamide
• Synonyms: N-(2-iodophenyl)-2-phenylacrylamide
• CAS NO: 1454769-81-3
• Molecular Weight: 349.171
• Mol File: 1454769-81-3.mol
• Article Data: 18

Chemical Properties

• CAS DataBase Reference: N-(2-iodophenyl)-2-phenylacrylamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-(2-iodophenyl)-2-phenylacrylamide(1454769-81-3)
• EPA Substance Registry System: N-(2-iodophenyl)-2-phenylacrylamide(1454769-81-3)

Safety Data

• Hazardous Substances Data: 1454769-81-3(Hazardous Substances Data)

Upstream product

• 3967-53-1 methyl tropate 
• 1865-29-8 2-phenyl-acrylic acid methyl ester 
• 101-41-7 benzeneacetic acid methyl ester 
• 103-82-2 phenylacetic acid 
• 615-43-0 2-iodophenylamine 
• 51491-68-0 2-phenylacrylyl chloride 
• 492-38-6 2-phenylacrylic acid 

Downstream Products

• 1454770-04-7 (E)-1-methyl-3-phenyl-3-styrylindolin-2-one 
• 1454769-82-4 N-(2-iodophenyl)-N-methyl-2-phenylacrylamide 

Relevant articles and documents

An approach to spirooxindoles: Via palladium-catalyzed remote C-H activation and dual alkylation with CH2Br2

A facile and efficient approach for the synthesis of spirooxindoles has been developed via the coupling of spirocyclic C,C-palladacycles with CH2Br2. The key spirocyclic palladacycles are generated catalytically via remote C-H activation. A range of spirooxindoles can be synthesized in good to excellent yields from readily available starting material.

Palladium-Catalyzed Domino Heck/Sulfination: Synthesis of Sulfonylated Hetero- And Carbocyclic Scaffolds Using DABCO-Bis(sulfur dioxide)

The synthesis of a broad variety of hetero- and carbocyclic scaffolds via a Pd-catalyzed domino Heck/SO2 insertion reaction is reported. This reaction utilizes DABSO, a safe and easy-to-handle alternative to SO2 gas. The reaction proceeds through a sulfin

Nickel-Catalyzed Arylcarbamoylation of Alkenes of N-(o-Iodoaryl)acrylamides with Nitroarenes via Reductive Aminocarbonylation: Facile Synthesis of Carbamoyl-Substituted Oxindoles

Nickel-catalyzed arylcarbamoylation reactions of alkenes of N-(o-haloaryl)acrylamides with CO and nitroarenes via reductive aminocarbonylation to produce carbamoyl-substituted oxindoles with an all-carbon quaternary stereogenic center are presented. Starting with N-(o-haloaryl)acrylamides, simple CO, and inexpensive nitroarenes and using a Ni catalyst, a dinitrogen-based ligand, a Zn reductant, a TMSCl additive, and a base system, this protocol enables the synthesis of various carbamoyl-substituted oxindoles and allows the efficient late-stage derivatization of valuable molecules.