Welcome to LookChem.com Sign In|Join Free

CAS

  • or

3967-53-1

Post Buying Request

3967-53-1 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

3967-53-1 Usage

General Description

A-(HYDROXYMETHYL)BENZENACETIC ACID METHYL ESTER is a chemical compound with the molecular formula C10H12O4. It is an ester of the phenylacetic acid and is used as an intermediate in the synthesis of pharmaceuticals and organic compounds. A-(HYDROXYMETHYL)BENZENACETIC ACID METHYL ESTER is white crystalline solid with a slight sweet odor and is soluble in organic solvents like ethanol and acetone. It is commonly used in the production of medications and is also used as a flavoring agent in the food industry. A-(HYDROXYMETHYL)BENZENACETIC ACID METHYL ESTER is also known for its potential therapeutic properties, including anti-inflammatory and antilipidemic actions.

Check Digit Verification of cas no

The CAS Registry Mumber 3967-53-1 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,9,6 and 7 respectively; the second part has 2 digits, 5 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 3967-53:
(6*3)+(5*9)+(4*6)+(3*7)+(2*5)+(1*3)=121
121 % 10 = 1
So 3967-53-1 is a valid CAS Registry Number.
InChI:InChI=1/C10H12O3/c1-13-10(12)9(7-11)8-5-3-2-4-6-8/h2-6,9,11H,7H2,1H3

3967-53-1SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 16, 2017

Revision Date: Aug 16, 2017

1.Identification

1.1 GHS Product identifier

Product name methyl 3-hydroxy-2-phenylpropanoate

1.2 Other means of identification

Product number -
Other names methyl 3-hydroxy-2-phenylpropionate

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:3967-53-1 SDS

3967-53-1Relevant articles and documents

Rational control of enzymatic enantioselectivity through solvation thermodynamics

Wescott, Charles R.,Noritomi, Hidetaka,Klibanov, Alexander M.

, p. 10365 - 10370 (1996)

The enantioselectivity of cross-linked crystals of γ-chymotrypsin in the transesterification of the medicinally important compound methyl 3-hydroxy-2-phenylpropionate (1) with propanol has been examined in a variety of organic solvents. The (k(cat)/K(M))(

Green Esterification of Carboxylic Acids Promoted by tert-Butyl Nitrite

Cheng, Xionglve,Jiang, Gangzhong,Li, Xingxing,Tao, Suyan,Wan, Xiaobing,Zhao, Yanwei,Zheng, Yonggao

supporting information, p. 2713 - 2718 (2021/06/25)

In this work, the green esterification of carboxylic acids promoted by tert-butyl nitrite has been well developed. This transformation is compatible with a broad range of substrates and exhibits excellent functional group tolerance. Various drugs and substituted amino acids are applicable to this reaction under near neutral conditions, with good to excellent yields.

Synthesis method of 3-hydroxy-2-phenylpropionic acid

-

Paragraph 0024-0026; 0030-0032; 0036-0038, (2019/12/25)

The invention discloses a synthetic method of 3-hydroxyl-2-phenylpropionic acid. The method comprises the following steps: mixing dimethyl sulfoxide, paraformaldehyde, potassium carbonate powder and methyl phenylacetate, heating to 85-95 DEG C, carrying out gas phase monitoring reaction, and cooling to room temperature when the GC content of the product methyl tropine is more than or equal to 70%;adjusting the pH value to be neutral, and performing reduced pressure distillation for desolvation; then adding methanol into the desolventized mixture, dropwise adding a sodium hydroxide solution, and reacting to obtain a mixed solution containing sodium tropine salt; adjusting the pH value of the mixed solution to 2-3, and completely reacting to obtain a crude product; and finally, recrystallizing the crude product sequentially by using methylbenzene of which the ratio of m product to m methylbenzene is 1: (4-6), methylbenzene/water of which the ratio of m product to m methylbenzene to m water is 1: (1-2): (4-6), and water of which the ratio of m product to m water is 1: (4-6) to obtain a pure product of 3-hydroxyl-2-phenylpropionic acid. According to the method, GC is adopted to monitor the reaction, control points are judged quickly and accurately, purification of methyl tropinate is not needed, operation procedures are reduced, and production cost is reduced. According to the method, the purity of the prepared 3-hydroxyl-2-phenylpropionic acid reaches 99% or above while the yield is ensured to reach 76.5% or above.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 3967-53-1