14552-00-2

Basic information

• Product Name: 1-Pyrrolizino-2,4-dinitrobenzene
• Synonyms: 1-(2,4-Dinitrophenyl)pyrrolidine;1-Pyrrolizino-2,4-dinitrobenzene
• CAS NO: 14552-00-2
• Molecular Formula: C₁₀H₁₁N₃O₄
• Molecular Weight: 237.22
• Mol File: 14552-00-2.mol
• Article Data: 23

Chemical Properties

• Melting Point: 66 °C
• Boiling Point: 408.6°Cat760mmHg
• Flash Point: 200.9°C
• Appearance: /
• Density: 1.414g/cm³
• Vapor Pressure: 6.94E-07mmHg at 25°C
• Refractive Index: 1.628
• PKA: -1.15±0.40(Predicted)
• CAS DataBase Reference: 1-Pyrrolizino-2,4-dinitrobenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pyrrolizino-2,4-dinitrobenzene(14552-00-2)
• EPA Substance Registry System: 1-Pyrrolizino-2,4-dinitrobenzene(14552-00-2)

Safety Data

• Hazardous Substances Data: 14552-00-2(Hazardous Substances Data)

Usage

Chemical structure

A nitroaromatic compound containing a pyrrolizine ring and two nitro groups

Toxicity

Highly toxic

Use

Research and as a sensitizing agent in the study of allergic contact dermatitis

Reactivity

Highly reactive

Effects on humans

Can cause severe skin irritation and allergic reactions

Classification

Potential carcinogen and mutagen

Regulation

Highly regulated and controlled in many countries

Restrictions

Use mainly restricted to research and industrial applications

Safety measures

Proper safety measures should be taken when handling and disposing of this compound.

InChI:InChI=1/C10H11N3O4/c14-12(15)8-3-4-9(10(7-8)13(16)17)11-5-1-2-6-11/h3-4,7H,1-2,5-6H2

Upstream product

• 123-75-1 pyrrolidine 
• 2486-07-9 2,4-dinitrophenyl phenyl ether 
• 13181-75-4 O-(2,4-dinitrophenyl) cyclohexanone oxime 
• 75735-29-4 (E)-O-(2,4-dinitrophenyl)benzaldoxime 
• 75735-26-1 O-(2,4-dinitrophenyl)-p-nitrobenzaldoxime 
• 13181-14-1 1-phenylethan-1-one O-(2,4-dinitrophenyl) oxime 
• 17188-67-9 diphenylmethanone O-(2,4-dinitrophenyl)oxime 
• 115828-58-5 4-methoxy-benzaldehyde-[O-(2,4-dinitro-phenyl)-seqtrans-oxime ] 
• 115806-86-5 O-(2,4-dinitrophenyl)-4'-bromobenzophenone oxime 
• 27091-32-3 2,2-dimethyl-1-(2,4-dinitrophenyl)aziridine 
• 115828-59-6 3-Bromo-benzaldehyde O-(2,4-dinitro-phenyl)-oxime 
• 97-00-7 1-chloro-2,4-dinitro-benzene 
• 25150-61-2 pyrrolidine hydrochloride 
• 13181-22-1 O-(2',4'-dinitrophenyl) 1,7,7-trimethyl-bicyclo[2.2.1]heptan-2-one oxime 

Downstream Products

• 2044-88-4 N-methyl-2,4-dinitroaniline 
• 5367-55-5 5-nitro-2-pyrrolidin-1-yl-aniline 
• 51-28-5 2,4-Dinitrophenol 

Relevant articles and documents

Photoredox catalyzed dealkylative aromatic halogen substitution with tertiary amines

A reaction of aromatic halides bearing electron-withdrawing groups with tertiary amines in the presence of an iridium catalyst under blue light irradiation is described. Products of the aromatic substitution of the halide by the dialkylamino fragment are

Pd(OAc)2-catalyzed dinitration reaction of aromatic amines

Taking advantage of Pd(OAc)2-catalyzed dinitration reactions with Bi(NO3)3·5H2O in trifluoroethanol (TFE) and trifluoroacetic acid (TFA), we have developed an efficient and practical method for the synthesis of secondary dinitro-aromatic amines. The products could be applied to the preparation of 5-amine-N-methyl-benzimidazolone, the azo-dyes, economic advantages. The method has also been expanded to the dinitration reaction of some tertiary aromatic amines.

Kinetics of snar reactions of 1-phenoxy-nitrobenzenes with aliphatic amines in toluene: Ring substituent and solvent effects on reaction pathways

Rate constants are reported for the reactions of a series of 4-substituted-1-phenoxy-2,6-dinitrobenzenes 1 and 6-substituted-1-phenoxy-2,4- dinitrobenzenes 2 activated by CF3, COOCH3, CN, NO 2 groups or by ring-nitrogen wi