1456-68-4

Basic information

• Product Name: 1,3,4-Thiadiazole, 2-(4-nitrophenyl)-5-phenyl-
• CAS NO: 1456-68-4
• Molecular Formula: C14H9N3O2S
• Molecular Weight: 283.31
• Mol File: 1456-68-4.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1,3,4-Thiadiazole, 2-(4-nitrophenyl)-5-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3,4-Thiadiazole, 2-(4-nitrophenyl)-5-phenyl-(1456-68-4)
• EPA Substance Registry System: 1,3,4-Thiadiazole, 2-(4-nitrophenyl)-5-phenyl-(1456-68-4)

Safety Data

• Hazardous Substances Data: 1456-68-4(Hazardous Substances Data)

Usage

Application

Pharmaceutical industry

Purpose

Synthesis of potential anti-tumor, anti-microbial, and anti-inflammatory agents

Biological activities

Diverse, contributing to its pharmacological properties

Structure

Thiadiazole ring with a nitrophenyl and phenyl group attached

Current status

Ongoing research for potential therapeutic applications and development of new drugs for various diseases

Upstream product

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Relevant articles and documents

One-pot synthesis of 1,3,4-thiadiazoles using Vilsmeier reagent as a versatile cyclodehydration agent

A simple and efficient synthetic method for the one-pot synthesis of 1,3,4-thiadiazoles utilizing Vilsmeier reagent was developed. In this method carboxylic acids and hydrazine were converted to 1,3,4-thiadiazoles in the presence of Vilsmeier reagent and Lawesson's reagent. The influence of the thionation reagent, solvent, temperature and time, in this reaction was discussed. The developed methodology for 1,3,4-thiadiazole synthesis has the advantage of simplicity, ambient reaction conditions, easy purification and good to excellent yield of products.

Synthesis of substituted 1,3,4-thiadiazoles using Lawesson's reagent

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