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14562-10-8

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14562-10-8 Usage

Description

2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde is a chemical compound with the molecular formula C13H10O2. It is a white solid at room temperature and belongs to the class of hydroxyaryl aldehydes. 2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde contains a hydroxyl group and a benzene ring, making it a versatile building block for the preparation of various organic compounds.

Uses

Used in Organic Synthesis:
2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde is used as a building block in organic synthesis for the preparation of various organic compounds. Its unique structure allows for the creation of a wide range of molecules with diverse applications.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde is used as a starting material for the synthesis of pharmaceuticals. Its presence in the molecular structure can contribute to the development of new drugs with potential therapeutic benefits.
Used in Dye Industry:
2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde is used as a starting material in the dye industry for the production of various dyes. Its chemical properties allow for the creation of dyes with specific color characteristics and stability.
Used in Fragrance Industry:
In the fragrance industry, 2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde is used as a starting material for the synthesis of various fragrances. Its unique chemical structure can contribute to the development of new scents with distinct olfactory properties.
Used in Antioxidant and Anti-inflammatory Research:
2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde has been studied for its potential antioxidant and anti-inflammatory properties. Its presence in molecular structures may contribute to the development of new compounds with health benefits and therapeutic applications.
It is important to handle 2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde with caution, as it can be hazardous if not properly managed and stored.

Check Digit Verification of cas no

The CAS Registry Mumber 14562-10-8 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 1,4,5,6 and 2 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 14562-10:
(7*1)+(6*4)+(5*5)+(4*6)+(3*2)+(2*1)+(1*0)=88
88 % 10 = 8
So 14562-10-8 is a valid CAS Registry Number.

14562-10-8SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 17, 2017

Revision Date: Aug 17, 2017

1.Identification

1.1 GHS Product identifier

Product name 2-hydroxy-3-phenylbenzaldehyde

1.2 Other means of identification

Product number -
Other names 2-Hydroxy-[1,1'-biphenyl]-3-carbaldehyde

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:14562-10-8 SDS

14562-10-8Relevant articles and documents

Ethylene polymerization by self-immobilized neutral nickel catalysts bearing allyl groups

Zhang, Dao,Jin, Guo-Xin,Hu, Ning-Hai

, p. 1570 - 1576 (2003)

[Ni(Ph)(PPh3)(N,O)] complexes containing phenyliminophenolato ligands (N,O) (1: N,O = A; 2: N,O = B; 3: N,O = C; 4: N,O = D; 5: N,O = E) have been synthesized and characterized. The molecular structure of 4 was determined by singlecrystal X-ray analysis. Complexes 2-5 bearing allyl groups have been investigated as self-immobilized catalysts for ethylene polymerization without the use of co-catalysts. The high ethylene polymerization activities of ca. 105 g·PE mol-1 Ni·h-1 and high molecular weight (MW ≈ 105) of polyethylene could be accomplished by changing the ligand structures and reaction conditions. The self-immobilization of catalysts brings about a dramatic increase in the catalytic activities of ethylene polymerization. Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2003.

Modifications at C(5) of 2-(2-Pyrrolidinyl)-Substituted 1,4-Benzodioxane Elicit Potent α4β2 Nicotinic Acetylcholine Receptor Partial Agonism with High Selectivity over the α3β4 Subtype

Bavo, Francesco,Pallavicini, Marco,Gotti, Cecilia,Appiani, Rebecca,Moretti, Milena,Colombo, Sara Francesca,Pucci, Susanna,Viani, Paola,Budriesi, Roberta,Renzi, Massimiliano,Fucile, Sergio,Bolchi, Cristiano

, p. 15668 - 15692 (2021/01/09)

A series of diastereomeric 2-(2-pyrrolidinyl)-1,4-benzodioxanes bearing a small, hydrogen-bonding substituent at the 7-, 6-, or 5-position of benzodioxane have been studied for α4β2 and α3β4 nicotinic acetylcholine receptor affinity and activity. Analogous to C(5)H replacement with N and to a much greater extent than decoration at C(7), substitution at benzodioxane C(5) confers very high α4β2/α3β4 selectivity to the α4β2 partial agonism. Docking into the two receptor structures recently determined by cryo-electron microscopy and site-directed mutagenesis at the minus β2 side converge in indicating that the limited accommodation capacity of the β2 pocket, compared to that of the β4 pocket, makes substitution at C(5) rather than at more projecting C(7) position determinant for this pursued subtype selectivity.

Synthesis and structure-activity relationship studies of hydrazide-hydrazones as inhibitors of laccase from trametes versicolor

Giurg, Miros?aw,Maniak, Halina,Matyja, Konrad,Talma, Micha?,Trusek, Anna

supporting information, (2020/03/23)

A series of hydrazide-hydrazones 1-3, the imine derivatives of hydrazides and aldehydes bearing benzene rings, were screened as inhibitors of laccase from Trametes versicolor. Laccase is a copper-containing enzyme which inhibition might prevent or reduce the activity of the plant pathogens that produce it in various biochemical processes. The kinetic and molecular modeling studies were performed and for selected compounds, the docking results were discussed. Seven 4-hydroxybenzhydrazide (4-HBAH) derivatives exhibited micromolar activity Ki = 24-674 μM with the predicted and desirable competitive type of inhibition. The structure-activity relationship (SAR) analysis revealed that a slim salicylic aldehyde framework had a pivotal role in stabilization of the molecules near the substrate docking site. Furthermore, the presence of phenyl and bulky tert-butyl substituents in position 3 in salicylic aldehyde fragment favored strong interaction with the substrate-binding pocket in laccase. Both 3- and 4-HBAH derivatives containing larger 3-tert-butyl-5-methyl- or 3,5-di-tert-butyl-2-hydroxy-benzylidene unit, did not bind to the active site of laccase and, interestingly, acted as non-competitive (Ki = 32.0 μM) or uncompetitive (Ki = 17.9 μM) inhibitors, respectively. From the easily available laccase inhibitors only sodium azide, harmful to environment and non-specific, was over 6 times more active than the above compounds.

Novel phenyl-substituted salicylaldimine metal titanium complexes, synthesis method and use method thereof

-

Paragraph 0042; 0047; 0048; 0049; 0050; 0051, (2019/01/08)

The invention discloses novel phenyl-substituted salicylaldimine metal titanium complexes, a synthesis method and a use method thereof. The novel phenyl-substituted salicylaldimine metal titanium complexes H1-H5 have ultra-high homopolymerization catalyti

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