304-06-3 Usage
Uses
2''-Hydroxybiphenyl-3-carboxylic Acid can be used as antibacterial agents.
Safety Profile
Poison by intraperitoneal route. When heated to decomposition it emits acrid smoke and irritating fume
Purification Methods
Dissolve the acid in ca 1 equivalent of saturated aqueous Na2CO3, filter and precipitate it by adding 0.8 equivalents of M HCl. Crystallise it from ethylene dichloride (charcoal), and sublime it at 0.1mm. [Brooks et al. J Chem Soc 661 1961.]
Check Digit Verification of cas no
The CAS Registry Mumber 304-06-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,0 and 4 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 304-06:
(5*3)+(4*0)+(3*4)+(2*0)+(1*6)=33
33 % 10 = 3
So 304-06-3 is a valid CAS Registry Number.
InChI:InChI=1/C13H10O3/c14-12-10(9-5-2-1-3-6-9)7-4-8-11(12)13(15)16/h1-8,14H,(H,15,16)
304-06-3Relevant articles and documents
General method for the synthesis of salicylic acids from phenols through palladium-catalyzed silanol-directed C-H carboxylation
Wang, Yang,Gevorgyan, Vladimir
, p. 2255 - 2259 (2015/02/19)
A silanol-directed, palladium-catalyzed C-H carboxylation reaction of phenols to give salicylic acids has been developed. This method features high efficiency and selectivity, and excellent functional-group tolerance. The generality of this method was demonstrated by the carboxylation of estrone and by the synthesis of an unsymmetrically o,o′-disubstituted phenolic compound through two sequential C-H functionalization processes.
