Cas 1456515-57-3,N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide

1456515-57-3

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Product Name: N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide
Synonyms: N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide
CAS NO:1456515-57-3
Molecular Formula:
Molecular Weight: 584.842
EINECS: N/A
Product Categories: N/A
Mol File: 1456515-57-3.mol
Article Data: 1

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: N/A
Refractive Index: N/A
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide(CAS DataBase Reference)
NIST Chemistry Reference: N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide(1456515-57-3)
EPA Substance Registry System: N-(2,6-dimethylphenyl)-2-methyl-2-(2-((1'R,5S,8a'S)-2',5,5',5',8a'-pentamethyl-4,4a',5,5',6',7',8',8a'-octahydro-3H,4'H-spiro[furan-2,1'-naphthalene]-5-yl)-N-phenylacetamido)propanamide(1456515-57-3)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 1456515-57-3(Hazardous Substances Data)

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Check Digit Verification of cas no

The CAS Registry Mumber 1456515-57-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,4,5,6,5,1 and 5 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 1456515-57:
(9*1)+(8*4)+(7*5)+(6*6)+(5*5)+(4*1)+(3*5)+(2*5)+(1*7)=173
173 % 10 = 3
So 1456515-57-3 is a valid CAS Registry Number.

1456515-57-3Upstream product

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1456515-57-3Relevant articles and documents

Derivatives of grindelic acid: From a non-active natural diterpene to synthetic antitumor derivatives

Reta, Guillermo F.,Chiaramello, Alejandra I.,Garcia, Celina,Leon, Leticia G.,Martin, Victor S.,Padron, Jose M.,Tonn, Carlos E.,Donadel, Osvaldo J.

, p. 28 - 38 (2013)

Using several reactions that include homologations and asymmetric epoxidations as well as Ugi and Huisgen couplings, we generated a small focused library of new derivatives from the labdane-type diterpene grindelic acid. These compounds were evaluated as cytotoxic agents against a panel of five human solid tumor cell lines (HBL-100, HeLa, SW1573, T-47D, and WiDr). The presence of the diamide functionalizations enhanced the cytotoxic effect. N-Benzyl-N-(1-(benzylamino)-2-methyl-1-oxopropan-2-yl)grindelicamide, proved to be the most active product in all cell lines tested, with values of 0.95 (±0.38) μM against HBL-100 cells. 2013 Elsevier Masson SAS. All rights reserved.

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