14568-90-2Relevant academic research and scientific papers
Sulfamic acid-functionalized magnetic Fe3O4 nanoparticles as an efficient and reusable catalyst for one-pot synthesis of α-amino nitriles in water
Kassaee,Masrouri, Hassan,Movahedi, Farnaz
experimental part, p. 28 - 33 (2012/01/04)
Grafting of chlorosulfuric acid on the amino-functionalized Fe 3O4 nanoparticles afforded sulfamic acid-functionalized magnetic Fe3O4 nanoparticles (SA-MNPs) as a novel organic-inorganic hybrid heterogeneous catalyst, which was characterized by XRD, FT-IR, TGA, TEM, and elemental analysis. The catalytic activity of SA-MNPs was probed through one-pot synthesis of α-amino nitriles via three-component couplings of aldehydes (or ketones), amines and trimethylsilyl cyanide in water, at room temperature. The heterogeneous catalyst could be recovered easily and reused many times without significant loss of its catalytic activity.
A New Synthesis of α-Aminonitriles Using Cyanotrimethylsilane
Prajapati, D.,Boruah, R. C.,Sandhu, J. S.,Baruah, J. N.
, p. 853 - 854 (2007/10/02)
α-Aminonitriles have been obtained in good yields from conjugated imines and cyanotrimethylsilane.There is no evidence of the formation of conjugate addition products or any other rearranged nitriles in this method.
