1456890-69-9

Basic information

• Product Name: mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid N-hydroxy succinimide ester
• Synonyms: mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid N-hydroxy succinimide ester
• CAS NO: 1456890-69-9
• Molecular Weight: 403.389
• Mol File: 1456890-69-9.mol

Chemical Properties

• CAS DataBase Reference: mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid N-hydroxy succinimide ester(CAS DataBase Reference)
• NIST Chemistry Reference: mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid N-hydroxy succinimide ester(1456890-69-9)
• EPA Substance Registry System: mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid N-hydroxy succinimide ester(1456890-69-9)

Safety Data

• Hazardous Substances Data: 1456890-69-9(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 18020-59-2 methyl 3-hydroxy-2-methylidene-3-phenylpropionate 
• 117746-42-6 5-[(2',5'-dioxo-1'-pyrrolidinyl)oxy]-5-oxopentanoyl chloride 
• 108-55-4 glutaric anhydride, 

Downstream Products

• 1456890-68-8 mono(1-phenyl-2-methoxycarbonyl-2-propenyl)glutaric acid 5S-carboxy-5-[bis(hydroxycarbonylmethyl)amino]pentylamide 

Relevant articles and documents

Templated alkylation of hexahistidine with Baylis-Hillman esters

Alkylation of one of the imidazole rings of hexahistidine with Baylis-Hillman esters tethered to nitrilotriacetate residue was achieved in aqueous solutions at neutral pH and at micromolar concentrations in the presence of Ni2+, Cu2+, or Zn2+ cations. The utility of the approach for selective functionalization of His-tagged recombinant proteins was demonstrated by attachment of a fluorescent label to recombinant protein A with an alkynyl group followed by a "click" 1,3-dipolar cycloaddition reaction.