145693-67-0 Usage
Uses
Used in Organic Synthesis:
(3S,4S)-(-)-BIS(DIPHENYLPHOSPHINO)PYRROLIDINE is used as a ligand in organic synthesis for its ability to facilitate asymmetric transformations, enabling chemists to control the stereochemistry of reaction products with precision.
Used in Asymmetric Catalysis:
In the field of asymmetric catalysis, (3S,4S)-(-)-BIS(DIPHENYLPHOSPHINO)PYRROLIDINE is used as a chiral ligand to create enantioselective catalysts, which are essential for producing chiral compounds with specific three-dimensional configurations.
Used in Hydrogenation Reactions:
(3S,4S)-(-)-BIS(DIPHENYLPHOSPHINO)PYRROLIDINE is used as a ligand in hydrogenation reactions to enhance the selectivity and efficiency of the process, leading to the production of desired chiral compounds with fewer side products.
Used in Hydroformylation Reactions:
This ligand is also utilized in hydroformylation reactions, where it helps in the selective formation of aldehydes from olefins and synthesis gas, contributing to the synthesis of various industrial chemicals and pharmaceuticals.
Used in Allylic Substitution Reactions:
(3S,4S)-(-)-BIS(DIPHENYLPHOSPHINO)PYRROLIDINE is used as a ligand in allylic substitution reactions to improve the selectivity of the process, allowing for the synthesis of specific isomers that are important in the production of pharmaceuticals and agrochemicals.
Used in the Design of Catalytic Processes:
In the chemical industry, (3S,4S)-(-)-BIS(DIPHENYLPHOSPHINO)PYRROLIDINE is used as a key component in the design of catalytic processes, where its ability to form stable complexes with transition metals is leveraged to create efficient and selective catalysts for a variety of chemical transformations.
Check Digit Verification of cas no
The CAS Registry Mumber 145693-67-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,6,9 and 3 respectively; the second part has 2 digits, 6 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 145693-67:
(8*1)+(7*4)+(6*5)+(5*6)+(4*9)+(3*3)+(2*6)+(1*7)=160
160 % 10 = 0
So 145693-67-0 is a valid CAS Registry Number.
145693-67-0Relevant academic research and scientific papers
Enantioselective Catalysis, 4. Synthesis of N-Substituted (R,R)-3,4-Bis(diphenylphosphino)pyrrolidines. The Use of their Rhodium Complexes for the Asymmetric Hydrogenation of α-(Acylamino)acrylic Acid Derivatives
Nagel, Ulrich,Kinzel, Elke,Andrade, Juan,Prescher, Guenter
, p. 3326 - 3343 (2007/10/02)
A simple synthesis of (R,R)-3,4-bis(diphenylphosphino)pyrrolidine (6a) and some N-substituted derivatives 6b-m is described. 6l and 6m are optically active tetraphosphanes, composed of two (R,R)-3,4-bis(diphenylphosphino)pyrrolidine units and a dicarboxylic residue.The structure of the parent compound 6a was determined by X-ray diffraction.From the phosphanes 6a-m the cationic 1,5-cyclooctadiene-bisphosphane-rhodium complexes 7a-m were prepared.The complexes 7l and 7m are ligand bridged bis(rhodium) dications.The complexes 7a-m were used for the asymmetric catalytic hydrogenation of the α-(acylamino)acrylic acid derivatives 9a-l.Enantiomeric excesses up to 100percent were achieved.Between 1 and 70 at the optical yields do not depend on the hydrogen pressure.The substrate/catalyst ratio can be as high as 50000/1.
