145741-63-5

Upstream product

• 34370-89-3 (3aR,5R,6R,6aR)-6-Benzyloxy-2,2-dimethyl-tetrahydro-furo[2,3-d][1,3]dioxole-5-carbaldehyde 
• 1099-45-2 ethyl (triphenylphosphoranylidene)acetate 
• 63593-02-2 3-O-benzyl-1,2-O-isopropylidene-α-D-ribo-pentodialdo-1,4-furanose 
• 14686-89-6 (1,2:5,6)-di-O-isopropylidene-D-gulose 
• 57099-04-4 3-O-benzyl-1,2-O-isopropylidene-α-D-allofuranose 
• 22331-21-1 1,2:5,6-di-O-isopropylidene-3-O-benzyl-α-D-allofuranose 
• 70798-12-8 1,2-O-isopropylidene-3-O-benzyl-α-D-ribofuranoside 
• 100-39-0 benzyl bromide 
• 867-13-0 diethoxyphosphoryl-acetic acid ethyl ester 
• 20590-57-2 1,2-O-isopropylidene-5-O-trityl-α-D-ribofuranose 

Downstream Products

• 145741-65-7 (-)-(2E)-(4R,5R,6R)-5-Benzyloxy-4,6-dihydroxy-7-(1',3'-dithiolan-2'-yl)hept-2-enoate 
• 145741-53-3 (+)-(1S,2S,3R,4S)-2-Benzyloxy-4-(2'-hydroxyethyl)cyclopentane-1,3-diol 
• 145741-67-9 (+)-(1S,2S,3R,4R)-Ethyl 5-benzyloxy-3-tert-butyldimethylsilyloxy-4-ethoxycarbonylmethylcyclopentan-1-ol 
• 145741-52-2 (+)-(1S,2S,3R,4S)-2-Benzyloxy-1,3-bis(tert-butyldimethylsilyloxy)-4-ethoxycarbonylmethylcyclopentane 
• 145741-66-8 (-)-(2E)-(4R,5S,6R)-5-Benzyloxy-4-tert-butyldimethylsilyloxy-7-(1',3'-dithiolan-2'-yl)-6-hydroxyhept-2-enoate 
• 108182-73-6 (E)-3-O-benzyl-5,6-dideoxy-1,2-O-isopropylidene-α-D-ribo-hept-5-enofuranose 

Relevant academic research and scientific papers

Synthesis and in vitro anticancer activity of penaresidin-related stereoisomeric analogues

A straightforward route to penaresidin-based derivatives with an unsubstituted alkyl side chain was developed. To construct these stereoisomeric azetidene-derived alkaloids, [3,3]-sigmatropic rearrangements followed by late stage olefin cross metathesis and an intramolecular nucleophilic type substitution were involved as the key transformations. The protected D-ribofuranose was chosen as the sole chiral source. The ability of target molecules to inhibit cancer cells proliferation was evaluated on a panel of five malignant cell lines.

Synthesis of new pseudo-C-nucleosides containing pyrazole rings in their structure

Synthetic approaches to new 4-(furanos-4- C -yl)-1 H -pyrazole and 3-(furanos-4- C -yl)-1 H -pyrazole derivatives are described, including its pyrazole-5-carboxylate derivative, which is a pyrazofurin analogue. Preparation of related 5-acetoxy-1-acetyl-1

Radical Cyclisation Reactions Leading to Polyhydroxylated Cyclopentane Derivatives: Synthesis of (1R,2R,3S,4R)- and (1S,2S,3R,4S)-4-Hydroxyethylcyclopentane-1,2,3-triol

The tetrol (-)-1 has been prepared from a derivative of (D)-allose 3.The stereoselective carbocyclization reaction (8->11) formed the key step in this sequence.The enantiomeric cyclopentane derivative (+)-1 was also prepared from compound 3.In this synthe

Total Synthesis of Griseolic Acid Derivatives from D-Glucose

Griseolic acid, 1, is a potent nonselective cyclic nucleotide-phosphodiesterase inhibitor isolated from Streptomyces griseoaurantiacus.Recently, preparation of several griseolic acid derivatives, including 3, has been reported.We have completed the chiral