1458674-51-5

Basic information

• Product Name: C₁₆H₂₀F₃NO₄
• Synonyms: C₁₆H₂₀F₃NO₄
• CAS NO: 1458674-51-5
• Molecular Weight: 347.334
• Mol File: 1458674-51-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₁₆H₂₀F₃NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₁₆H₂₀F₃NO₄(1458674-51-5)
• EPA Substance Registry System: C₁₆H₂₀F₃NO₄(1458674-51-5)

Safety Data

• Hazardous Substances Data: 1458674-51-5(Hazardous Substances Data)

Upstream product

• 1458674-48-0 C₁₁H₁₈F₃NO₄ 
• 1310680-43-3 C₉H₁₄F₃NO₄ 
• 100-39-0 benzyl bromide 
• 24424-99-5 di-tert-butyl dicarbonate 

Downstream Products

• 1458674-53-7 C₁₁H₁₂F₃NO₂*C₂HF₃O₂ 

Relevant articles and documents

Stereo-regulated synthesis of peptides containing a β-trifluoromethyl- β-amino acid

For the chemical conversions of a β-trifluoromethyl-β-amino acid ((S)-4,4,4-trifluoro-3-aminobutyric acid, 1), such as the N-terminus protection with benzyloxycarbonyl or tert-butoxycarbonyl group, the C-terminus protection with benzyl or tert-butyl group, and peptide elongation at the both termini, highly practical protocols were established. Through these conversions, the stereochemistry of 1 and/or its condensation counterpart was maintained. Because the protocols developed here are indispensable for the application of 1 in peptide engineering, they would expand the utility of 1 and its derivatives.