145915-29-3

Usage

Uses

Used in Organic Synthesis:
Benzenesulfonyl chloride, 4-bromo-2-methoxy-, is used as a reagent in organic synthesis for the preparation of sulfonamides and other bioactive molecules. Its ability to introduce the sulfonyl group into organic molecules makes it a valuable tool in the synthesis of various compounds.
Used in Pharmaceutical Research:
In pharmaceutical research, Benzenesulfonyl chloride, 4-bromo-2-methoxy-, is utilized as a reagent for the preparation of bioactive molecules. Its sulfonating properties enable the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
Benzenesulfonyl chloride, 4-bromo-2-methoxy-, is used as an intermediate in the production of agrochemicals. Its role in the synthesis of various agrochemical compounds contributes to the development of effective products for agricultural applications.
Used in Dye Production:
In the dye industry, Benzenesulfonyl chloride, 4-bromo-2-methoxy-, is employed as an intermediate for the production of dyes. Its involvement in the synthesis of dye molecules allows for the creation of a wide range of colors and properties in various dye products.

Upstream product

• 2398-37-0 3-methoxyphenyl bromide 
• 59557-91-4 4-bromo-2-methoxyaniline 

Relevant academic research and scientific papers

Synthesis method of 4-bromo-2-methoxybenzenesulfonyl chloride

The invention relates to a synthesis method of 4-bromo-2-methoxybenzenesulfonyl chloride. The synthesis method comprises the following steps of: adding cuprous chloride into water, dropwise adding thionyl chloride at 0-10 DEG C, and reacting at room temperature for 16-24 hours to form a standby solution A; adding 4-bromine-2-methoxyaniline into an acidic solvent at 0-10 DEG C, dropwise adding a sodium nitrite solution into the 4-bromine-2-methoxyaniline acidic solution system under the condition of controlling the temperature at 0-10 DEG C, and reacting for 30 minutes to 1 hour while keeping the temperature at -5 DEG C to 0 DEG C to form a standby solution B; finally, slowly dropwise adding the standby solution B into the standby solution A under the condition of controlling the temperature at 0-10 DEG C, enable the standby solution B and the standby solution A to be fully mixed and react, then raising the temperature to the room temperature of 25 DEG C, reacting for 8-24 hours, then introducing ice water, performing DCM extraction, backwashing, drying and spin-drying, and then performing purifying to obtain the compound 4-bromo-2-methoxybenzenesulfonyl chloride.

NOVEL TETRAZOLE COMPOUNDS AND THEIR USE IN THE TREATMENT OF TUBERCULOSIS

The invention relates to a compound of Formula (I) or a pharmaceutically acceptable salt thereof and their use in therapy, for example in the treatment of mycobacterial infections or in the treatment of diseases caused by mycobacterium, such as tuberculosis.

PIPERAZINE DERIVATIVES USEFUL FOR THE TREATMENT OF GASTROINTESTINAL DISORDERS

The invention provides compounds of formula (I) or pharmaceutically acceptable salts thereof, wherein Ra, Rb, Rc, Rd, Re, Rf and Y are as defined in the specification. The compounds are partial or full agonists at the growth hormone secretagogue (GHS) receptors . Pharmaceutical compositions comprising the compounds, methods of preparing the compounds, uses of the compounds and methods involving the compounds are also provided.

Amino heterocyclyl inhibitors of 11-beta-hydroxy steroid dehydrogenase type 1

The present invention relates to compounds with the formula (I), or a pharmaceutically acceptable salt thereof: The invention also relates to pharmaceutical compositions comprising the compounds of formula (I) or formula (II) and methods of treating a condition that is mediated by the modulation of 11-β-hsd-1, the method comprising administering to a mammal an effective amount of a compound of formula (I) or formula (II).

PHENYL SULFONAMIDE ENDOTHELIN ANTAGONISTS

Compounds of the formula STR1 inhibit the activity of endothelin. The symbols are defined as follows: R 1, R 2 and R. sup.3 are each independently(a) hydrogen, except that R. sup.1 is other than hydrogen;(b) alkyl, alkenyl, alkynyl, alkoxy, cycloalkyl, cycloalkylalkyl, cycloalkenyl, cycloalkenylalkyl, aryl, aryloxy, aralkyl or aralkoxy, any of which may be substituted with Z 1, Z 2 and Z. sup.3 ;(c) halo;(d) hydroxyl;(e) cyano; (f) nitro; (g)--C(O)H or--C(O)R 6 ;(h)--CO 2 H or--CO 2 R 6 ; (i)--SH,--S(O) n R 6,--S(O) m--OH,--S(O) m--OR 6,--O--S(O) m--R 6,--O--S(O) m OH or--O--S(O) m--OR. sup.6 ;(j)--Z. sup.4--NR 7 R 8 ; or (k)--Z 4--N(R 11--Z 5--NR 9 R 10 ; and the remaining symbols are as defined in the specification.