1459161-35-3

Basic information

• Product Name: tert-butyl (2S)-2-((1R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate
• Synonyms: tert-butyl (2S)-2-((1R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate
• CAS NO: 1459161-35-3
• Molecular Weight: 413.43
• Mol File: 1459161-35-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: tert-butyl (2S)-2-((1R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: tert-butyl (2S)-2-((1R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate(1459161-35-3)
• EPA Substance Registry System: tert-butyl (2S)-2-((1R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-5-oxo-2,5-dihydro-1H-pyrrole-1-carboxylate(1459161-35-3)

Safety Data

• Hazardous Substances Data: 1459161-35-3(Hazardous Substances Data)

Upstream product

• 141293-14-3 N-(tert-butoxycarbonyl)pyrrol-2(5H)-one 
• 53557-94-1 5-styryl-4-nitro-3-methylisoxazole 

Downstream Products

• 1459161-51-3 (S)-5-((R)-2-(3-methyl-4-nitroisoxazol-5-yl)-1-phenylethyl)-1H-pyrrol-2(5H)-one 

Relevant articles and documents

Organocatalyzed asymmetric vinylogous Michael addition of α,β-unsaturated γ-butyrolactam

Highly efficient asymmetric vinylogous 1,6-Michael addition of α,β-unsaturated γ-butyrolactam to 3-methyl-4-nitro-5-alkenyl- isoxazoles and Michael addition to trichloromethyl ketones by using a chiral quinine-derived squaramide organocatalyst were described, giving products with high diastereo- and enantioselectivities (up to >25:1 dr and 96% ee).