145919-42-2 Usage
General Description
29-methylidene-2,3-oxidosqualene is a chemical compound that plays a crucial role in the biosynthesis of steroids and triterpenoids. It is an important intermediate in the biosynthetic pathway of cholesterol, a vital component of cell membranes and a precursor to steroid hormones. 29-methylidene-2,3-oxidosqualene is also involved in the synthesis of other biologically active molecules, including brassinosteroids and oxidosqualene-derived triterpenoids with diverse functions in plants. 29-methylidene-2,3-oxidosqualene is produced in organisms such as plants and fungi through a series of enzymatic reactions from squalene, and it can serve as a starting point for the formation of a wide variety of bioactive compounds with important physiological and pharmacological properties.
Check Digit Verification of cas no
The CAS Registry Mumber 145919-42-2 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,5,9,1 and 9 respectively; the second part has 2 digits, 4 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 145919-42:
(8*1)+(7*4)+(6*5)+(5*9)+(4*1)+(3*9)+(2*4)+(1*2)=152
152 % 10 = 2
So 145919-42-2 is a valid CAS Registry Number.
InChI:InChI=1/C31H50O/c1-8-10-11-22-29(16-9-2)23-15-21-27(4)18-13-12-17-26(3)19-14-20-28(5)24-25-30-31(6,7)32-30/h8-10,17-18,20,23,30H,2,11-16,19,21-22,24-25H2,1,3-7H3/b10-8-,26-17+,27-18+,28-20+,29-23-
145919-42-2Relevant articles and documents
Asymmetric synthesis of a mechanism-based inhibitor of oxidosqualene cyclase
Madden,Prestwich
, p. 5488 - 5491 (1994)
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Potency and inactivation rates of analogues of an irreversible inhibitor of vertebrate oxidosqualene cyclase
Madden, Brenda A.,Prestwich, Glenn D.
, p. 309 - 314 (2007/10/03)
Truncated, 22(23)-dihydro, and fluorinated analogues of (3S)-29-methylidene-2,3-oxidosqualene (29-MOS) were prepared and inhibitory potencies and rates of inactivation of rat oxidosqualene cyclase were measured. Rapid mechanism-based enzyme inactivation was observed for both methylidene and difluoromethylidene analogues with complete pro-side chains, but not for truncated analogues.