1459246-62-8

Basic information

• Product Name: 4-phenyl-4-vinyl-1,3-dioxolan -2-one
• Synonyms: 4-phenyl-4-vinyl-1,3-dioxolan -2-one
• CAS NO: 1459246-62-8
• Molecular Weight: 190.199
• Mol File: 1459246-62-8.mol
• Article Data: 25

Chemical Properties

• CAS DataBase Reference: 4-phenyl-4-vinyl-1,3-dioxolan -2-one(CAS DataBase Reference)
• NIST Chemistry Reference: 4-phenyl-4-vinyl-1,3-dioxolan -2-one(1459246-62-8)
• EPA Substance Registry System: 4-phenyl-4-vinyl-1,3-dioxolan -2-one(1459246-62-8)

Safety Data

• Hazardous Substances Data: 1459246-62-8(Hazardous Substances Data)

Upstream product

• 13735-81-4 1-styrenyloxytrimethylsilane 
• 1159837-56-5 1,2-dihydroxy-2-phenyl-3-butene 
• 1826-67-1 vinyl magnesium bromide 
• 582-24-1 1-phenyl-2-hydroxyethanone 
• 100-42-5 styrene 
• 70-11-1 α-bromoacetophenone 
• 98-86-2 acetophenone 
• 32315-10-9 bis(trichloromethyl) carbonate 

Downstream Products

• 1610616-91-5 (S)-4-phenyl-4-vinyl-1,3-dioxolane 
• 1610616-90-4 (R)-4-phenyl-4-vinyl-1,3-dioxolane 
• 1663513-73-2 (2S,4R)-2-methyl-4-phenyl-4-vinyl-1,3-dioxolane 
• 1644060-41-2 (2R,4R)-2-methyl-4-phenyl-4-vinyl-1,3-dioxolane 

Relevant articles and documents

Regioselective Organocatalytic Formation of Carbamates from Substituted Cyclic Carbonates

A highly regioselective catalytic approach has been developed towards carbamates derived from cyclic organic carbonates by reaction of the latter with amine reagents under organocatalytic control. For various combinations of carbonate and amine substrates, an organocatalyst (TBD: 1,5,7-triazabicyclo[4.4.0]dec-5-ene) was used to increase the reaction kinetics while exerting excellent regioselective control. The current method is the first general approach towards the control over the regioselectivity of this reaction using a wide variety of easily accessed substituted organic carbonates. (Figure presented.) .

Palladium-Catalyzed Regio- And Stereoselective Cross-Coupling of Vinylethylene Carbonates with Ketimine Esters to Generate (Z)-Tri- And Tetra-substituted Allylic Amino Acid Derivatives

Herein we report the palladium-catalyzed regio- and stereoselective cross-coupling of vinylethylene carbonates with ketimine esters to construct allylic amino acid scaffolds. This operationally simple protocol furnished (Z)-tri- and tetra-substituted ally

Palladium-catalyzed stereoselective (3 + 2) cycloaddition of vinylethylene carbonates with cyclicN-sulfonyl ketimines

A diastereoselective (3 + 2) cycloaddition ofN-sulfonyl ketimines with vinylethylene carbonates (VECs) in the presence of Pd2dba3·CHCl3and PPh3has been developed. The reaction of various substituted VECs and diverse cyclicN-sulfonyl ketimines proceeded smoothly under mild conditions, giving highly functionalized oxazolidine frameworks in good to excellent yields with moderate to good diastereoselectivities. With the use of spiroketal-based diphosphine SKP as a chiral ligand, an asymmetric version of the current (3 + 2) cycloaddition was achieved, and chiral products were obtained in >99% ee in most cases.

Asymmetric Synthesis of 2,2-Difluorotetrahydrofurans through Palladium-Catalyzed Formal [3+2] Cycloaddition

The asymmetric synthesis of 2,2-difluorinated tetrahydrofurans was accomplished via enantioselective formal [3+2] cycloaddition catalyzed by palladium. The asymmetric reaction between gem-difluoroalkenes and racemic vinyl epoxides or vinylethylene carbonates resulted in the formation of enantioenriched 2,2-difluorotetrahydrofurans with an enantioselectivity up to 98 %. Notably, the reaction used the readily available (R)-BINAP as the ligand at a low loading and yielded a wide variety of difluorinated products in moderate to high yields. Both chiral diastereomers could be obtained in a single sequence.