14593-25-0

Usage

Uses

Used in Pharmaceutical Industry:
4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride is used as a chemical intermediate for the synthesis of pharmaceutical compounds. Its unique structure, including the phenyl group, acetate, chlorine atom, and methylamino group, allows for the development of new drugs with potential therapeutic applications.
Used in Agricultural Industry:
In agriculture, 4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride may be utilized as an intermediate in the production of agrochemicals, such as pesticides or herbicides. Its chemical properties can contribute to the development of effective and targeted solutions for crop protection.
Used in Research and Development:
4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride is used as a research compound for studying its chemical properties and potential applications in various fields. Researchers can explore its reactivity, stability, and interactions with other compounds to discover new uses and optimize its synthesis process.
It is crucial to handle and use 4-[1-Chloro-2-(methylamino)ethyl]phenyl Acetate Hydrochloride with care, adhering to proper safety protocols and regulations to minimize potential hazards. Its diverse applications across industries highlight the importance of understanding and managing its properties to ensure safe and effective use.

InChI:InChI=1/C11H14ClNO2.ClH/c1-8(14)15-10-5-3-9(4-6-10)11(12)7-13-2;/h3-6,11,13H,7H2,1-2H3;1H

Upstream product

• 5985-28-4 (+/-)-Synephrine hydrochloride 
• 75-36-5 acetyl chloride 

Relevant academic research and scientific papers

Mechanism for the stabilization in vivo of the aziridine precursor 2-(4-acetoxyphenyl)-2-chloro-N-methyl-ethylammonium chloride by serum proteins

Oral and intraperitoneal administration of 2-(4-acetoxyphenyl)-2-chloro-N-methylethylammonium chloride (Compound A), an analogue of phenyl aziridine precursors that occur in the shrub Salsola tuberculatiformis Botsch., had a contraceptive effect on female Wistar rats with a concomitant decrease in total body, uterus, and ovary mass and an increase in adrenal mass. Compound A elicited a Type II difference spectrum and inhibited the Type I deoxycorticosterone (DOC) induced difference spectrum of sheep adrenal cytochrome P450c11 in a manner similar to that of S2, a biologically active fraction isolated from S. tuberculatiformis. The effects of Compound A on the spectral properties of P450c11 were diminished with time in PBS. ELectrospray mass spectrometry (ES-MS) indicated that the rate of cyclization of Compound A to the corresponding aziridine followed a time course similar to the attenuation of cytochrome P450c11 inhibition. It was concluded that the aziridine precursor, Compound A, rather than aziridine itself, was the inhibiting agent of sheep adrenal P450c11. Addition of sheep and rat plasma prevented the attenuation of the effect of Compound A on the spectral properties of cytochrome P450c11. Subsequent ES-MS analysis indicated that Compound A was stabilized in plasma by sex hormone binding globulin and corticosteroid binding globulin. These results suggest a mechanism whereby natural plant products, which are highly reactive and unstable in vitro, can be stabilized by binding to plasma proteins, and so remain biologically active in vivo.