145930-40-1

Basic information

• Product Name: Oxazole, 5-(3-nitrophenyl)-2-phenyl-
• CAS NO: 145930-40-1
• Molecular Formula: C15H10N2O3
• Molecular Weight: 266.256
• Mol File: 145930-40-1.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: Oxazole, 5-(3-nitrophenyl)-2-phenyl-(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 5-(3-nitrophenyl)-2-phenyl-(145930-40-1)
• EPA Substance Registry System: Oxazole, 5-(3-nitrophenyl)-2-phenyl-(145930-40-1)

Safety Data

• Hazardous Substances Data: 145930-40-1(Hazardous Substances Data)

Upstream product

• 7023-81-6 2-diazo-1-(3-nitrophenyl)ethanone 
• 100-47-0 benzonitrile 
• 762-42-5 dimethyl acetylenedicarboxylate 
• 20662-88-8 2-phenyloxazole 
• 645-00-1 m-iodonitrobenzene 
• 2835-06-5 phenylglycin 
• 121-89-1 3-Nitroacetophenone 
• 65-85-0 benzoic acid 
• 40513-40-4 2-amino-1-(3-nitro-phenyl)-ethanone 

Relevant articles and documents

N -Bromosuccinimide as a Brominating Agent for the Transformation of N -H (or N -Benzyl) Ketoaziridines into Oxazoles

A novel procedure for the direct synthesis of 2,5-diaryloxazoles starting from N-H ketoaziridines is described. The method proceeds via the in situ formation of N-bromoketoaziridines in the presence of N-bromosuccinimide followed by the generation of intermediate azomethine ylides. A plausible mechanism for this transformation is proposed.

Direct arylations on water: Synthesis of 2,5-disubstituted oxazoles balsoxin and texaline

An efficient two-step palladium catalysed synthesis of 2,5-disubstituted oxazoles is reported. The Royal Society of Chemistry.

Formation of Acyl-Substituted Nitrile Ylides by Rh2(OAc)4-Catalyzed Decomposition of α-Diazocarbonyl Compounds in Nitriles

The Rh2(OAc)4-catalyzed reactions of α-diazocarbonyl compounds in nitrile in the presence of dimethyl acetylenedicarboxylate (DMAD) gave oxazole and pyrrole derivatives.The formation of the oxazole derivatives is explained in terms of the 1,5-cyclization of an acyl-substituted nitrile ylide intermediate, and the formation of the pyrrole derivatives is explained by the 1,3-dipolar cycloaddition of the same intermediate with DMAD.The regiochemistry of the cycloaddition of the acyl-substituted nitrile ylide with methyl propiolate showed that the contribution of an allenyl-type resonance structure plays an important role in the acyl-substituted nitrile ylide reaction.