145936-41-0

Upstream product

• 24313-88-0 3,4,5-Trimethoxyaniline 
• 64-18-6 formic acid 
• 145936-38-5 2,4-diamino-5-methyl-6[[(3,4,5-trimethoxyphenyl)amino]methyl]pyrido[2,3-d]pyrimidine 
• 101810-73-5 2,4-diamino-5-methylpyrido<2,3-d>pyrimidine-6-carbonitrile 

Downstream Products

• 151477-78-0 N-(2,4-Diamino-5-methyl-5,6,7,8-tetrahydro-pyrido[2,3-d]pyrimidin-6-ylmethyl)-N-(3,4,5-trimethoxy-phenyl)-formamide 

Relevant academic research and scientific papers

Synthesis of 5-methyl-5-deaza nonclassical antifolates as inhibitors of dihydrofolate reductases and as potential antipneumocystis, antitoxoplasma, and antitumor agents

A series of 2,4-diamino-5-methyl-6-(anilinomethyl)pyrido[2,3- d]pyrimidines 4-9 were synthesized as 5-deaza nonclassical antifolates containing trimethoxy, dichloro-, or trichlorophenyl substitutions and a N- H, N-CH3, or N-CHO at the 10-positi