146008-39-1

Basic information

• Product Name: (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-6-octanoyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester
• CAS NO: 146008-39-1
• Molecular Weight: 905.133
• Mol File: 146008-39-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-6-octanoyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-6-octanoyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester(146008-39-1)
• EPA Substance Registry System: (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-6-octanoyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester(146008-39-1)

Safety Data

• Hazardous Substances Data: 146008-39-1(Hazardous Substances Data)

Upstream product

• 138682-84-5 zaragozic acid A 
• 146008-36-8 (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-6-((E)-(4S,6S)-4,6-dimethyl-oct-2-enoyloxy)-4-hydroxy-7-(1-methoxy-1-methyl-ethoxy)-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester 
• 144358-24-7 <1S-<1α(4R*,5R*),3α,4β,5α,6α(2E,4R*,6R*),7β>>-1-<4-(acetyloxy)-5-methyl-3-methylene-6-phenylhexyl>4,6,7-trihydroxy-2,8-dioxabicyclo<3.2.1>octane-3,4,5-tricarboxylic acid, 6-(4,6-dimethyl-2-octenoate), 3,4,5-tris(1,1-dimethylethyl) ester 
• 71432-55-8 2-tert-butyl-1,3-diisopropylisourea 
• 124-07-2 Octanoic acid 
• 146008-37-9 (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4,6-dihydroxy-7-(1-methoxy-1-methyl-ethoxy)-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid tri-tert-butyl ester 
• 111-64-8 n-octanoic acid chloride 
• 623-66-5 octanoic acid anhydride 

Downstream Products

• 144357-94-8 (1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-3-methylene-6-phenyl-hexyl)-4,7-dihydroxy-6-octanoyloxy-2,8-dioxa-bicyclo[3.2.1]octane-3,4,5-tricarboxylic acid 

Relevant articles and documents

Structure-Activity Relationships of C1 and C6 Side Chains of Zaragozic Acid A Derivatives

Systematic modification of the C6 acyl side chain of zaragozic acid A, a potent squalene synthase inhibitor, was undertaken to improve its biological activity.Simplification of the C6 side chain to the octanoyl ester has deleterious effects; increasing th