146039-09-0

Basic information

• Product Name: Phenethyl-phosphorimidic acid triethyl ester
• Synonyms: Phenethyl-phosphorimidic acid triethyl ester
• CAS NO: 146039-09-0
• Molecular Weight: 285.323
• Mol File: 146039-09-0.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Phenethyl-phosphorimidic acid triethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phenethyl-phosphorimidic acid triethyl ester(146039-09-0)
• EPA Substance Registry System: Phenethyl-phosphorimidic acid triethyl ester(146039-09-0)

Safety Data

• Hazardous Substances Data: 146039-09-0(Hazardous Substances Data)

Upstream product

• 103-63-9 1-phenyl-2-bromoethane 
• 55419-66-4 trifluoroacetic acid 2-phenylethyl ester 
• 60-12-8 2-phenylethanol 
• 6926-44-9 phenethyl azide 
• 122-52-1 triethyl phosphite 

Downstream Products

• 53050-54-7 phenethylamine; toluene-4-sulfonate 
• 24070-12-0 2-methyl-N-phenethylpropan-1-amine 
• 3647-71-0 N-benzyl-2-phenylethylamine 
• 3240-95-7 N-benzylidene-2-phenylethanamine 
• 64-04-0 phenethylamine 
• 156-28-5 2-phenylethylamine hydrochloride 
• 57673-91-3 diethyl phenethylphosphoramidate 
• 91406-83-6 N-Isobutyliden-β-phenaethylamin 

Relevant articles and documents

A convergent one-pot synthesis of secondary amines via aza-Wittig reaction

Secondary amines are obtained in moderate-good yields by reduction of crude imines prepared from N-alkyltriethoxyiminophosphoranes and aldehydes via the aza-Wittig reaction. N-Alkyltriethoxyiminophosphoranes are synthesized by one-pot azidation of alkyl bromides followed by Staudinger reaction.

Optimized procedures for one-pot conversion of alkyl bromides into amines via the Staudinger reaction

New optimized procedures for transforming primary and secondary alkyl bromides into the corresponding primary amine salts have been elaborated. Essential modifications of azidation and deprotection of intermediate triethoxyphosphine alkylimides resulted in substantial improvement of the overall yields. Conversion of ammonium tosylates and hydrochlorides into free amines in a nonaqueous medium is described.

One-Pot Transformation of Alkyl Bromdes into Primary Amines via the Staudinger Reaction

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