146097-08-7 Usage
Molecular Weight
176.19 g/mol This is the mass of one mole of 1-Trityl-1H-1,2,4-triazole-5-carbaldehyde, measured in grams.
Appearance
Pale yellow solid This refers to the physical appearance of the compound, which is a pale yellow solid at room temperature.
Melting Point
158-160°C This is the temperature range at which the compound changes from a solid to a liquid state.
Solubility
Slightly soluble in water, soluble in common organic solvents This indicates how well the compound dissolves in different solvents, with slightly soluble in water meaning it does not dissolve well, and soluble in common organic solvents meaning it dissolves easily in many organic solvents.
Derivative of Triazole
A five-membered heterocyclic compound containing three nitrogens and two carbons This explains that 1-Trityl-1H-1,2,4-triazole-5-carbaldehyde is derived from triazole, a heterocyclic compound with three nitrogen atoms and two carbon atoms in its ring.
Use in Organic Synthesis
Reagent for the preparation of various heterocyclic compounds This indicates that 1-Trityl-1H-1,2,4-triazole-5-carbaldehyde is commonly used as a reagent in organic synthesis to prepare other heterocyclic compounds.
Use in Pharmaceutical and Agrochemical Synthesis
Building block in the synthesis of pharmaceuticals and agrochemicals This means that 1-Trityl-1H-1,2,4-triazole-5-carbaldehyde can be used as a starting material or building block in the synthesis of pharmaceuticals and agrochemicals.
Potential Applications
Materials science and nanotechnology This suggests that 1-Trityl-1H-1,2,4-triazole-5-carbaldehyde has potential applications in the fields of materials science and nanotechnology, although specific uses are not mentioned.
Check Digit Verification of cas no
The CAS Registry Mumber 146097-08-7 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,0,9 and 7 respectively; the second part has 2 digits, 0 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 146097-08:
(8*1)+(7*4)+(6*6)+(5*0)+(4*9)+(3*7)+(2*0)+(1*8)=137
137 % 10 = 7
So 146097-08-7 is a valid CAS Registry Number.
146097-08-7Relevant articles and documents
Synthesis, SAR and selectivity of 2-acyl- and 2-cyano-1-hetarylalkyl- guanidines at the four histamine receptor subtypes: A bioisosteric approach
Geyer, Roland,Igel, Patrick,Kaske, Melanie,Elz, Sigurd,Buschauer, Armin
, p. 72 - 81 (2014/01/06)
In the search for potential bioisosteres of the 4-imidazolyl ring in acylguanidines (e.g. UR-AK24), known to possess affinity to several histamine receptor subtypes (HxR, x = 1-4), and cyanoguanidine-type H 4R agonists (e.g. UR-PI376
The design and synthesis of inhibitors of imidazoleglycerol phosphate dehydratase as potential herbicides
Cox,Hawkes,Bellini,Ellis,Barrett,Swanborough,Russell,Walker,Barnes,Knee,Lewis,Davies
, p. 297 - 311 (2007/10/03)
The discovery and exploration of a new class of broad-spectrum postemergent herbicides with a novel mode of action, namely the disruption of histidine biosynthesis via inhibition of imidazoleglycerol phosphate dehydratase (IGPD; E.C. 4.2.1.19), are described. Clear structural similarities between the first member, produced during an attempt to produce analogues of glyphosate, and intermediates in histidine biosynthesis were noted. Several series of targets were designed, to mimic both the enzyme substrate and a putative reaction intermediate, and synthesised. Some examples were found to be both extremely potent inhibitors of the enzyme, having K(i) values as low as 0·3 nM, and phloem-mobile herbicides with levels of weed control similar to those shown by glyphosate. Further logical progress awaits a high-resolution X-ray structure determination of an enzyme-inhibitor complex.
