146118-95-8Relevant articles and documents
Total synthesis of pumiliotoxins 209F and 251D via late-stage, nickel-catalyzed epoxide-alkyne reductive cyclization
Woodin, Katrina S.,Jamison, Timothy F.
, p. 7451 - 7454 (2007)
(Chemical Equation Presented) Pumiliotoxins 209F and 251D were synthesized using highly selective nickel-catalyzed epoxide-alkyne reductive cyclizations as the final step. The exocyclic (Z)-alkene found in the majority of the pumiliotoxins was formed ster
Total synthesis of 1-deoxy-7,8a-di-epi-castanospermine and formal synthesis of pumiliotoxin-251D
Sultane, Prakash R.,Mohite, Amar R.,Bhat, Ramakrishna G.
supporting information, p. 5856 - 5858 (2013/01/13)
A concise and efficient synthesis of (6R,7S,8R,8aS)-6,7,8- trihydroxyindolizidine (1-deoxy-7,8a-di-epi-castanospermine) 2 is described. The synthesis employs cross metathesis in building the key intermediate 9 and is used effectively in constructing indol
Three-step synthesis of cyclopropyl peptidomimetics
Dunlap, Norma,Lankford, Kevin R.,Pathiranage, Anuradha Liyana,Taylor, Jessica,Reddy, Nikhil,Gouger, Daniel,Singer, Phillip,Griffin, Kent,Reibenspies, Joseph
supporting information; experimental part, p. 4879 - 4881 (2011/12/05)
An efficient approach to novel cyclopropyl peptidomimetics has been developed. The synthetic route involves a cyclopropanation using ethyl (dimethylsulfuranylidene)acetate (EDSA) as the key step and affords a cyclopropyl peptidomimetic core in three steps
