146174-52-9

Upstream product

• 3185-99-7 Methyl p-tolyl sulfone 
• 60682-95-3 1-(diethoxyphosphorylmethylsulfonyl)-4-methylbenzene 
• 177213-26-2 (E)-1-((3-(benzyloxy)prop-1-en-1-yl)sulfonyl)-4-methylbenzene 
• 154581-58-5 (E/Z)-3-benzyloxy-1-(4-tolylsulfonyl)-2-propene 
• 19790-60-4 3-Benzyloxypropanal 
• 185811-93-2 1,6-bis(benzyloxy)-4-(4-tolylsulfonyl)-5-hexen-3-ol 

Downstream Products

• 139883-68-4 5-<2-benzyloxyethyl>-2(5H)-furanone 
• 146174-60-9 5-<2-benzyloxyethyl>-2-oxo-4-(4-tolylsulfonyl)tetrahydrofuran 

Relevant academic research and scientific papers

(Alkoxyallyl)sulfones as enal β-anion equivalents. Synthesis of 5-substituted 2(5H)-furanones

2(5H)-Furanones 14 may be prepared in a four-step sequence starting from (alkoxyallyl)sulfone 10 and aldehydes.

1-Benzyloxy-3-(p-tolylsulfonyl)propene as an acrolein β-anion equivalent. Synthesis of 4-substituted 2-butenolides

Lithiation of 1-benzyloxy-3-(p-tolylsulfonyl)propene 6 and reaction with aldehydes give alcohols 7. Sequential hydrolysis-cyclization, oxidation and DBU-mediated elimination of dine elements of p-TolSO2H gives 4-substituted 2-butenolides 10 in good overall yield.