14618-33-8Relevant articles and documents
N-alkylation of phthalimide, carboxamide, and sulfonamides by oxdation-reduction condensation using di-tert-butyl-1,4-benzoquinone and alkyl diphenylphosphinite
Mukaiyama, Teruaki,Aoki, Hidenori
, p. 142 - 143 (2005)
Various N-alkylamides were obtained in high yields under mild conditions by treating alkyl diphenylphosphinite with phthalimide, carboxamide or sulfonamides in the presence of 2,6-di-tert-butyl-1,4-benzoquinone (DBBQ) by oxdation-reduction condensation. C
Electrochemical approach to trifluoroacetamide synthesis from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) catalyzed by B12complex
Moniruzzaman, Mohammad,Yano, Yoshio,Ono, Toshikazu,Hisaeda, Yoshio,Shimakoshi, Hisashi
, (2021/03/09)
One-pot synthetic approach to produce trifluoroacetamide has been developed using an electrochemical method with the B12 complex as a catalyst under mild conditions, in open air at room temperature. Thirty examples of trifluoroacetamide were synthesized from 1,1,1-trichloro-2,2,2-trifluoroethane (CFC-113a) in moderate to good yields. This user-friendly strategy is compatible with a broad range of trifluoroacetamide syntheses.
Catalytic reduction of amides to amines by electrophilic phosphonium cations via FLP hydrosilylation
Augurusa, Alessandra,Mehta, Meera,Perez, Manuel,Zhu, Jiangtao,Stephan, Douglas W.
supporting information, p. 12195 - 12198 (2016/10/21)
A catalytic methodology for the conversion of amides to amines is reported. Of the 25 examples described, 14 examples involve the reduction of N-trifluoroacetamides to the corresponding trifluoroethylamines. These reductions are achieved by catalytic hydrosilylation of the amide mediated by an electrophilic phosphonium cation (EPC) catalyst.
