14621-84-2

Basic information

• Product Name: Methane-d2, diazo-(6CI,7CI,8CI,9CI)
• Synonyms: Diazomethane-d2; Dideuteriodiazomethane
• CAS NO: 14621-84-2
• Molecular Formula: CH₂N₂
• Molecular Weight: 44.06
• Mol File: 14621-84-2.mol
• Article Data: 5

Chemical Properties

• CAS DataBase Reference: Methane-d2, diazo-(6CI,7CI,8CI,9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Methane-d2, diazo-(6CI,7CI,8CI,9CI)(14621-84-2)
• EPA Substance Registry System: Methane-d2, diazo-(6CI,7CI,8CI,9CI)(14621-84-2)

Safety Data

• Hazard Codes: 3:
• Safety Statements: x. See also DIAZOMETHANE." target="_blank">An explosive. When heated to decomposition it emits toxic fumes of NOx. See also DIAZ
• Hazardous Substances Data: 14621-84-2(Hazardous Substances Data)

Upstream product

• 42366-72-3 N-methyl-d₃-N-nitroso-para-toluenesulfonamide 
• 80-11-5 N-methyl-N-nitrosotoluene-p-sulfonamide 
• 684-93-5 1-methyl-1-nitrosourea 
• 68426-45-9 N-nitroso-N-trideuteriomethyl-urea 

Downstream Products

• 13423-15-9 3-methyltetrahydrofuran 
• 96-47-9 2-methyltetrahydrofuran 
• 1664-98-8 paraformaldehyde-d2 
• 628-28-4 butyl methyl ether 
• 6795-87-5 2-butyl methyl ether 
• 115-10-6 Dimethyl ether 
• 628-32-0 ethylpropylether 
• 625-44-5 isobutyl methyl ether 
• 540-67-0 ethyl methyl ether 
• 557-17-5 methyl propyl ether 
• 625-54-7 2-butyl ethyl ether 
• 87829-55-8 Ru₃(CO)7(CH₂CCCH(CH₃)2)(C⁽²⁾H₂)(P(C₆H₅)2) 
• 79825-70-0 [²H₃]methyl benzoate 
• 1309445-23-5 C₂₁H₁₅⁽²⁾H₃N₂O₄ 

Relevant articles and documents

Efficient, scalable and economical preparation of tris(deuterium)- and 13C-labelled N-methyl-N-nitroso-p-toluenesulfonamide (Diazald) and their conversion to labelled diazomethane

A method for the preparation of multi-gramme quantities of N-methyl-d3-N-nitroso-p-toluenesulfonamide (Diazald-d3) and N-methyl-13C-N-nitroso-p-toluenesulfonamide (Diazald-13C) and their conversion to diazomethane-d2 and diazomethane-13C, respectively, is presented. This approach uses robust and reliable chemistry, and critically, employs readily commercially available and inexpensivemethanol as the label source. Several reactions of labelled diazomethane are also reported, including alkene cyclopropanation, phenolmethylation and α-diazoketone formation, as well as deuteriumscrambling in the preparation of diazomethane-d2 and subsequent methyl esterification of benzoic acid.

Methyl Trideuteriomethyl (E)-(α-Bromoarylidene)malonates: Simple Stereochemical Probes in Nucleophilic Vinylic Substitution near the Retention/Stereoconvergence Borderline

Methyl trideuteriomethyl (E)-(α-bromo-p-methyl- and -p-nitrobenzylidene)malonates (4 and 5) were prepared.These electrophilic bromo olefins are activated to vinylic substitution by ywo chemically identical but isotopically distinguishable CO2Me groups.The

Stereochemical studies on the reactions catalyzed by the PLP-dependent enzyme 1-aminocyclopropane-1-carboxylate deaminase

The stereochemical course of 1-aminocyclopropane-1-carboxylate deaminase which catalyzes the fragmentation of the cyclopropane substrate to alpha -ketobutyrate and ammonia has been unraveled with the help of substrates stereospecifically labeled with deuterium and/or tritium, and this has afforded important information about the process occurring at the active site during enzymatic conversion.