14623-49-5Relevant academic research and scientific papers
Synthesis and biological evaluation of novel 5,6-dihydrobenzo[h]quinazoline derivatives as FLT3 inhibitors
Ding, Lei,Fan, Weizheng,Jiao, Xiaoyu,Tang, Chunlei,Zhang, Qing,Zhao, Kuantao,Zhou, Ying
, (2021/12/22)
Fms-like tyrosine kinase 3 (FLT3) is widely expressed and often mutated in acute myeloid leukemia (AML), which makes it an important target for the treatment of AML. The structure-based synthesis and biological evaluation of 5,6-dihydrobenzo[h]quinazoline
5-6 -dihydrobenzo [h] quinazoline compound and application thereof
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, (2021/09/08)
The invention discloses 5-6 -dihydrobenzo [h] quinazoline compound and application thereof, and belongs to the field of medicines. I, 5-dihydrobenzo [6 -] quinazoline compounds represented by the formula h of the invention have excellent inhibition FLT3 i
