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N-(4-fluorophenyl)-4-methylbenzothioamide is a chemical with a specific purpose. Lookchem provides you with multiple data and supplier information of this chemical.

146274-09-1

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146274-09-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 146274-09-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,4,6,2,7 and 4 respectively; the second part has 2 digits, 0 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 146274-09:
(8*1)+(7*4)+(6*6)+(5*2)+(4*7)+(3*4)+(2*0)+(1*9)=131
131 % 10 = 1
So 146274-09-1 is a valid CAS Registry Number.

146274-09-1Relevant articles and documents

Mixed bases mediated synthesis of thioamides in water

Li, Jiao,Ren, Xuanhe,Li, Ganzhong,Liang, Helong,Zhao, Yajie,Wang, Zhiwu,Li, Heng,Yuan, Bingxin

, p. 229 - 237 (2020/02/20)

A mixed bases mediated protocol is developed to synthesize thioamides from N-aryl or N-alkylamide, aldehyde and elemental sulfur in water. This reaction requires no addition of external oxidant and avoids large excess of amides. Various functional groups

Method for promoting elemental sulfur to synthesize thioamide by mixed alkali in water phase

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Paragraph 0069-0072, (2020/07/13)

The invention provides a method for promoting elemental sulfur to synthesize a thioamide compound by a mixed alkali in a water phase, and belongs to the field of organic synthesis. According to the method, an aldehyde compound and an amide compound are us

Thioamide derivative and preparation method thereof

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Paragraph 0110-0112, (2018/11/04)

The invention discloses a thioamide derivative. The structural formula of the thioamide derivative is represented by the formula (I) or the formula (II). The invention also provides a preparation method of the thioamide derivative. According to the preparation method, alkali metal salts are taken as the alkalis, amines are directly coupled with alkenes and sulfur, and by selecting the alkali, twodifferent thioamide derivatives represented by the formula (I) and the formula (II) can be prepared from same raw materials. The provided preparation method has the advantages that the raw materials are cheap and easily available, the synthesis method is simple, and the cost is largely reduced. The provided thioamide derivatives can be used in fields such as bioactive molecules, drug synthesis, and the like, and has a wide application range.

Base-Controlled Three Component Reactions of Amines, Elemental Sulfur, and Styrenes: Synthesis of Thioamides under Metal-Free Conditions

Zhang, Pingshun,Chen, Wanzhi,Liu, Miaochang,Wu, Huayue

, p. 14269 - 14276 (2018/11/25)

Three component reactions of olefins, amines, and sulfur were studied. Thioamidation of styrenes is base-controlled, and 2-phenylethanethioamides and benzothioamides were obtained selectively in the presence of two different bases. This protocol offers a simple and efficient procedure for the synthesis of thioamides.

Hybrids of privileged structures benzothiazoles and pyrrolo[2,1-c] [1,4]benzodiazepin-5-one, and diversity-oriented synthesis of benzothiazoles

Subhas Bose,Idrees, Mohd.,Todewale, Ismail K.,Jakka,Venkateswara Rao

scheme or table, p. 27 - 38 (2012/07/01)

Privileged structures like Benzothiazole and Pyrrolobenzodiazepine offer wonderful opportunity to explore in anti-cancer drug discovery as a mean to counter drug-resistance problem. BT-PBD hybrids and diverse BT derivatives have been synthesized and their in vitro cytotoxic activities were screened against five cancer cell lines have been discussed. The novel compounds showed promising results as compared with the marketed drug etoposide and could well be used in future anti-cancer drug development studies.

Synthesis, anticancer activity and docking of some substituted benzothiazoles as tyrosine kinase inhibitors

Bhuva, Hemal A.,Kini, Suvarna G.

experimental part, p. 32 - 37 (2011/10/09)

Protein tyrosine kinases occupy a central position in the control of cellular proliferation and its inactivation might lead to the discovery of a new generation anticancer compounds. Substituted benzothiazoles have been found to mimic the ATP-competitive

Antimycobacterial activity of 3'- and 4'-fluorothiobenzanilides

Waisser,Kunes,Odlerova,Roman,Kubicova,Horak

, p. 193 - 195 (2007/10/03)

On the basis of a preliminary study of the antimycobacterial activity of thiobenzanilides, a group of 3/-fluoro- and 4/fluorothiobenzanilides has been synthesized and tested against Mycobacterium tuberculosis, M. kansasii, M. avium and M. fortuitum. The r

Novel disease-modifying antirheumatic drugs. I. Synthesis and antiarthritic activity of 2-(4-methylphenyl)benzothiazoles

Hori,Tsukamoto,Imamura,Ohashi,Saito,Yoshino

, p. 2387 - 2390 (2007/10/02)

A series of 2-(4-methylphenyl)benzothiazoles was synthesized and evaluated using an adjuvant-induced arthritic rat model. This class of desired compounds affecting the immune response was found using hemagglutination assay. 4-Acetoxy-2-(4-methylphenyl)ben

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