14629-62-0

Upstream product

• 96-09-3 styrene oxide 
• 617-86-7 triethylsilane 
• 60-12-8 2-phenylethanol 
• 55453-17-3 triethyl((1-methoxy-2-methylprop-1-en-1-yl)oxy)silane 
• 1112-54-5 vinyltriethylsilane 
• 4249-72-3 2-phenoxy-1-phenylethanol 
• 101-97-3 Ethyl 2-phenylethanoate 
• 18296-01-0 triethylsilyl formate 
• 18406-24-1 1-(triethylsilyloxy)-4-methoxybenzene 
• 3558-60-9 1-methoxy-2-phenylethane 
• 994-30-9 triethylsilyl chloride 
• 122-78-1 phenylacetaldehyde 
• 89597-33-1 (E)-1-methoxy-1-(triethylsiloxy)propene 

Downstream Products

• 103-45-7 acetic acid phenethyl ester 
• 100-41-4 ethylbenzene 
• 1861-04-7 2-deuterioethylbenzene 
• 60-12-8 2-phenylethanol 

Relevant academic research and scientific papers

Mechanism of the dehydrogenative silylation of alcohols catalyzed by cationic gold complexes: An experimental and theoretical study

The catalytic activity both of cationic [(XDPP)Au][X] (XDPP=bis-2,5- diphenylphosphole xantphos X=BF4) and of the isolated gold hydride complex [(XDPP)2Au2H][OTf] in the dehydrogenative silylation process is presented. A p

Use of Silylated Formiates as Hydrosilane Equivalents

The present invention relates to a method for preparing organic compounds of formula (I) by reaction between a silylated formiate of formula (II) and an organic compound in the presence of a catalyst and optionally of an additive. The invention also relates to use of the method for preparing organic compounds of formula (I) for the preparation of reagents for fine chemistry and for heavy chemistry, as well as in the production of vitamins, pharmaceutical products, adhesives, acrylic fibres, synthetic leathers, and pesticides.

Chemoselective Deoxygenation of 2° Benzylic Alcohols through a Sequence of Formylation and B(C6F5)3-Catalyzed Reduction

A sequence of formylation and B(C6F5)3-catalyzed reduction of the resulting formate with Et3SiH enables the chemoselective deoxygenation of secondary benzylic alcohols. Primary benzylic and tertiary non-benzylic alcohols are not reduced by this protocol. The formyl group fulfills a double role as activator and self-sacrificing protecting group. The deoxygenation of these formates is fast and can be carried out in the presence of other potentially reducible groups. Neighboring-group participation was found in the deoxygenation of certain diol motifs.

Cationic Dirhodium Complexes Bridged by 2-Phosphinopyridines Having an Exquisitely Positioned Axial Shielding Group: A Molecular Design for Enhancing the Catalytic Activity of the Dirhodium Core

This report describes a strategy to create highly electrophilic dirhodium catalysts. The electrophilicity of lantern-Type dirhodium complexes is generally decreased by the coordination of a ligand to the axial site, which often causes a reduction in the catalytic activity. We designed and synthesized a series of cationic dirhodium complexes bridged by 2-diarylphosphinopyridines having a bulky 2,4,6-Triisopropylphenyl (Tip) group that can prevent the attack of external molecules to the closest axial site. Theoretical calculations indicated that the Tip group weakly interacts with the axial site but hardly reduces the electrophilicity of the dirhodium core. The complexes served as excellent catalyst precursors for the dehydrogenative silylation of alcohols using hydrosilanes under mild conditions and a low metal loading, producing the silyl ethers in higher yields in comparison to conventional dirhodium complexes.

Hydrosilylation of Carbonyls Catalyzed by Hydridoborenium Borate Salts: Lewis Acid Activation and Anion Mediated Pathways

The electronically unsaturated three-coordinated hydridoborenium cations [LBH]+[HB(C6F5)3]-(1) and [LBH]+[B(C6F5)4]-(2), supported by a bis(phosphinimino)amide ligand, were found to be excellent catalysts for hydrosilylation of a range of aliphatic and ar

Controlling Sugar Deoxygenation Products from Biomass by Choice of Fluoroarylborane Catalyst

The feedstocks from biomass are defined and limited by nature, but through the choice of catalyst, one may change the deoxygenation outcome. We report divergent but selective deoxygenation of sugars with triethylsilane (TESH) and two fluoroarylborane catalysts, B(C6F5)3 and B(3,5-CF3)2C6H3)3 (BAr3,5-CF3). To illustrate, persilylated 2-deoxyglucose shows exocyclic C-O bond cleavage/reduction with the less sterically congested BAr3,5-CF3, whereas endocyclic C-O bond cleavage/reduction predominates with the more Lewis acidic B(C6F5)3. Chiral furans and linear polyols can be selectively synthesized depending on the catalysts. Mechanistic studies demonstrate that the resting states of these catalysts are different.

Pt-catalyzed O-silylation of oximes by tri-substituted organosilanes

Silylated derivatives of oximes are important intermediates in organic synthesis, and have found application in the preparation of various nitrogen containing compounds including nitriles, amines, nitrones, and hydroxylamines. An efficient method for the

Iron-Catalyzed Silylation of Alcohols by Transfer Hydrosilylation with Silyl Formates

An iron catalyst is shown for the first time to promote transfer hydrosilylation with silyl formates and is utilized for the silylation of alcohols. Attractive features of this protocol include the use of an earth-abundant transition-metal catalyst, mild reaction conditions, and the release of gases as the only byproducts (H 2 and CO 2).

Silylation of O-H bonds by catalytic dehydrogenative and decarboxylative coupling of alcohols with silyl formates

The silylation of O-H bonds is a useful methodology in organic synthesis and materials science. While this transformation is commonly achieved by reacting alcohols with reactive chlorosilanes or hydrosilanes, we show herein for the first time that silylformates HCO2SiR3 are efficient silylating agents for alcohols, in the presence of a ruthenium molecular catalyst.

A Versatile Iridium(III) Metallacycle Catalyst for the Effective Hydrosilylation of Carbonyl and Carboxylic Acid Derivatives

A versatile iridium(III) metallacycle catalysed rapidly and selectively the reduction of a large array of challenging esters and carboxylic acids as well as various ketones and aldehydes. The reactions proceeded in high yields at room temperature by hydrosilylation followed by desilylation. Although the reactions of various aldehydes and ketones resulted exclusively in alcohols, the hydrosilylation of esters led to alcohols or ethers, depending on the type of substrate. Regarding the carboxylic acids, again the nature of the reagent controlled the outcome of the hydrosilylation reaction, either alcohols or aldehydes being formed.