146305-30-8

Basic information

• Product Name: Benzoic acid, 4-(benzoylamino)-, 2-[(methylamino)thioxomethyl]hydrazide
• CAS NO: 146305-30-8
• Molecular Formula: C16H16N4O2S
• Molecular Weight: 328.395
• Mol File: 146305-30-8.mol
• Article Data: 4

Chemical Properties

• CAS DataBase Reference: Benzoic acid, 4-(benzoylamino)-, 2-[(methylamino)thioxomethyl]hydrazide(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoic acid, 4-(benzoylamino)-, 2-[(methylamino)thioxomethyl]hydrazide(146305-30-8)
• EPA Substance Registry System: Benzoic acid, 4-(benzoylamino)-, 2-[(methylamino)thioxomethyl]hydrazide(146305-30-8)

Safety Data

• Hazardous Substances Data: 146305-30-8(Hazardous Substances Data)

Upstream product

• 94-09-7 p-aminoethylbenzoate 
• 98-88-4 benzoyl chloride 
• 736-40-3 N-benzoylbenzocaine 
• 146305-29-5 N-[4-(hydrazinylcarbonyl)phenyl]benzamide 
• 556-61-6 methyl thioisocyanate 

Downstream Products

• 360559-33-7 4-[5-(2,4-dichloro-benzylsulfanyl)-4-methyl-4H-[1,2,4]triazol-3-yl]-phenylamine 
• 360559-32-6 4-(5-benzylsulfanyl-4-methyl-4H-[1,2,4]triazol-3-yl)-phenylamine 
• 149622-77-5 5-(4-aminophenyl)-2,4-dihydro-4-methyl-3H-1,2,4-triazole-3-thione 

Relevant articles and documents

Synthesis of some 3-(Arylalkylthio)-4-alkyl/aryl-5-(4-aminophenyl)-4H-1,2, 4-triazole derivatives and their anticonvulsant activity

A series of novel 3-{[(substituted phenyl)methyl]thio}-4-alkyl/aryl-5-(4- aminophenyl)-4H-1,2,4-triazoles 11-20 and several related Schiff's bases, 3-{[(substituted phenyl)-methyl]thio}-4-alkyl/aryl-5-{[[(substituted phenyl/5-nitro-2-furyl)methylene]amino

Some 3-Thioxo/Alkylthio-1,2,4-triazoles with a Substituted Thiourea Moiety as Possible Antimycobacterials

A series of novel N-alkyl/aryl-N'-[4-(4-alkyl/aryl-2,4-dihydro-3H-1,2,4-triazole-3-thione-5-yl)phenyl]thioureas 1-19 and three S-alkylated representatives of the former, N-alkyl/aryl-N'-[4-(3-aralkylthio-4-alkyl/aryl-4H-1,2,4-triazole-5-yl)phenyl]thioureas 20-22, were synthesized and tested for antimycobacterial activity against Mycobacterium tuberculosis H37Rv as well as Mycobacterium fortuitum ATCC 6841 which is a rapid growing opportunistic pathogen. Compounds 4 and 9-11 were found to possess the same MIC value with that of Tobramycin against M. fortuitum ATCC 6841 whereas 1-3 and 21 had positive response against M. tuberculosis H37Rv at varying degrees. Compound 21 was identified as the most potent derivative of the 1-22 series by an MIC value of 6.25 μg/ml and selectivity index of 1.6