146326-27-4Relevant articles and documents
Indole derivatives as a new class of steroid 5α-reductase inhibitors
Takami, Hitoshi,Koshimura, Hirokazu,Kishibayashi, Nobuyuki,Ishii, Akio,Nonaka, Hiromi,Aoyama, Shiro,Kase, Hiroshi,Kumazawa, Toshiaki
, p. 5047 - 5052 (2007/10/03)
A series of indole derivatives with varied substituents on the α,β- unsaturated double bond were synthesized and evaluated for their ability to inhibit rat prostatic 5α-reductase. Compounds possessing an ethyl substituent at the β-position of the double b