146330-83-8Relevant academic research and scientific papers
Regiochemical Control of the Ring Opening of 1,2-Epoxides by Means of Chelating Processes. 5. Synthesis and Reactions of Some 2,3-Epoxy-1-alkanol Derivatives
Chini, Marco,Crotti, Paolo,Flippin, Lee A.,Gardelli, Christina,Giovani, Elena,et al.
, p. 1221 - 1227 (1993)
In order to study the effect of a remote polar functionality on the regiochemistry of the ring opening of aliphatic epoxides, the synthesis and some nucleophilic additions (methanolysis, azidolysis, and aminolysis) of suitable 2,3-epoxy-1-alkanol derivati
Direct, iridium-catalyzed enantioselective and regioselective allylic etherification with aliphatic alcohols
Ueno, Satoshi,Hartwig, John F.
, p. 1928 - 1931 (2008/12/22)
(Chemical Equation Presented) From alcohol to ether: Iridium-catalyzed allylations yield α chiral ether derivatives directly from aliphatic alcohols with a simple alkali metal base (see equation). These reactions form ethers from primary, secondary, and tertiary alkoxides with high enantioselectivity. By-products from isomerization were suppressed by the use of an alkyne additive.
