42134-55-4

Basic information

• Product Name: 2-Propen-1-ol, 3-cyclohexyl-, (Z)-
• CAS NO: 42134-55-4
• Molecular Formula: C9H16O
• Molecular Weight: 140.225
• Mol File: 42134-55-4.mol
• Article Data: 63

Chemical Properties

• CAS DataBase Reference: 2-Propen-1-ol, 3-cyclohexyl-, (Z)-(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Propen-1-ol, 3-cyclohexyl-, (Z)-(42134-55-4)
• EPA Substance Registry System: 2-Propen-1-ol, 3-cyclohexyl-, (Z)-(42134-55-4)

Safety Data

• Hazardous Substances Data: 42134-55-4(Hazardous Substances Data)

Upstream product

• 695-12-5 vinylcyclohexane 
• 6117-80-2 1,4-butenediol 
• 931-51-1 cyclohexylmagnesiumchloride 
• 132350-01-7 2-(1-chloro-2-propenyl)-1,3,2-dioxaborinane 
• 109-65-9 1-bromo-butane 
• 172990-75-9 1-acetoxy-3-cyclohexyl-trans-2-propene 
• 26429-99-2 methyl (2E)-3-cyclohexylprop-2-enoate 
• 56453-86-2 (E)-3-cyclohexylprop-2-enoic acid 
• 110-54-3 hexane 
• 5664-17-5 cyclohexylallene 
• 931-48-6 2-cyclohexylacetylene 
• 2043-61-0 cyclohexanecarbaldehyde 
• 18521-02-3 (Z)-ethyl 3-cyclohexylacrylate 
• 16722-09-1 trimethylsilyloxirane 

Downstream Products

• 137151-58-7 (E)-3-cyclohexyl-2-propenyl 1-(trimethylsilyl)vinyl ether 
• 111902-61-5 (2R,3R)-3-cyclohexyl-2,3-epoxypropan-1-ol 
• 111843-46-0 methyl (2S,3R)-3-cyclohexyloxiranecarboxylate 
• 144102-19-2 (E)-1-Phenyl-4-cyclohexyl-but-3-en-1-ol 
• 140439-82-3 syn-3-cyclohexyl-4-hydroxy-4-phenyl-1-butene 
• 140439-82-3 anti-1-phenyl-2-cyclohexylbut-3-en-1-ol 
• 144102-19-2 (E)-4-Cyclohexyl-1-phenyl-but-3-en-1-ol 
• 131719-68-1 1-[(E)-3-bromo-1-propenyl]cyclohexane 
• 1202701-75-4 ((1S,2R,3R)-2-cyclohexyl-3-iodocyclopropyl)methanol 
• 131719-41-0 (Z)-3-bromo-1-cyclohexylprop-1-ene 
• 58649-22-2 (Z)-(3-chloro-1-propen-1-yl)cyclohexane 
• 58649-21-1 (E)-(3-chloroprop-1-en-1-yl)cyclohexane 
• 37868-74-9 (E)-3-cyclohexylpropenal 
• 147159-44-2 (Z)-3-cyclohexylpropenal 

Relevant articles and documents

Ligand-controlled cobalt-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes

The Co-catalyzed remote hydroboration and alkene isomerization of allylic siloxanes were realized by a ligand-controlled strategy. The remote hydroboration with dcype provided borylethers, while xantphos favored the formation of silyl enol ethers.

Multicatalytic approach to one-pot stereoselective synthesis of secondary benzylic alcohols

One-pot procedures bear the potential to rapidly build up molecular complexity without isolation and purification of consecutive intermediates. Here, we report multicatalytic protocols that convert alkenes, unsaturated aliphatic alcohols, and aryl boronic acids into secondary benzylic alcohols with high stereoselectivities (typically >95:5 er) under sequential catalysis that integrates alkene cross-metathesis, isomerization, and nucleophilic addition. Prochiral allylic alcohols can be converted to any stereoisomer of the product with high stereoselectivity (>98:2 er, >20:1 dr).

Catalytic Asymmetric Allylic Substitution with Copper(I) Homoenolates Generated from Cyclopropanols

By using copper(I) homoenolates as nucleophiles, which are generated through the ring-opening of 1-substituted cyclopropane-1-ols, a catalytic asymmetric allylic substitution with allyl phosphates is achieved in high to excellent yields with high enantioselectivity. Both 1-substituted cyclopropane-1-ols and allylic phosphates enjoy broad substrate scopes. Remarkably, various functional groups, such as ether, ester, tosylate, imide, alcohol, nitro, and carbamate are well tolerated. Moreover, the present method is nicely extended to the asymmetric construction of quaternary carbon centers. Some control experiments argue against a radical-based reaction mechanism and a catalytic cycle based on a two-electron process is proposed. Finally, the synthetic utilities of the product are showcased by means of the transformations of the terminal olefin group and the ketone group.