14636-31-8Relevant academic research and scientific papers
Catalyst-free, facile, and an efficient synthesis of α-aminonitriles employing Zn(CN)2 as an ecofriendly cyanating agent
Shah, Sakshi,Singh, Baldev
, p. 151 - 156 (2012)
An efficient and eco-friendly method has been developed for the synthesis of α-aminonitriles via one-pot three-component condensation of carbonyl compounds, amines, and Zn(CN)2 under mild conditions. This protocol has the features of use of inexpensive, ecofriendly readily available, effective cyanide source, high yield, and simple work-up procedure.
Cyano-borrowing: Titanium-catalyzed direct amination of cyanohydrins with amines and enantioselective examples
Li, Qian,Li, Qing-Hua,Li, Wan-Fang,Li, Zhao-Feng,Liu, Tang-Lin,Peng, Yun-Gui,Ren, Li-Qing,Tao, Jing
supporting information, p. 651 - 654 (2020/01/28)
The direct amination of cyanohydrins with amines via a catalytic cyano-borrowing reaction was developed. The transformation features broad substrate scope, excellent functional group compatibility, and very mild and simple operations. Moreover, a titanium
Zinc triflate a water compatible, green catalyst in one pot three-component efficient synthesis of α-Amino nitriles
Suresh,Chand, Subhash,Sandhu, Jagir S.
, p. 853 - 856 (2013/08/23)
α-Amino nitriles are synthesized in one pot three-component coupling of aldehydes, amines and trimethylsilyl cyanide using catalytic amount of zinc triflate at ambient temperature.
A New Synthesis of α-Aminonitriles Using Cyanotrimethylsilane
Prajapati, D.,Boruah, R. C.,Sandhu, J. S.,Baruah, J. N.
, p. 853 - 854 (2007/10/02)
α-Aminonitriles have been obtained in good yields from conjugated imines and cyanotrimethylsilane.There is no evidence of the formation of conjugate addition products or any other rearranged nitriles in this method.
