146368-07-2

Usage

Uses

Used in Organic Synthesis:
1-Ethyl-2,3,3-Trimethyl-Indoleninium-5-Sulfonate is used as a synthetic building block for the development of new organic compounds. Its chemical properties allow it to be a versatile component in the synthesis of a wide range of molecules, including pharmaceuticals, agrochemicals, and other specialty chemicals.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, 1-Ethyl-2,3,3-Trimethyl-Indoleninium-5-Sulfonate is used as a key intermediate in the synthesis of various drug molecules. Its unique structure and reactivity enable the development of novel therapeutic agents with improved efficacy and selectivity.
Used in Agrochemical Industry:
1-Ethyl-2,3,3-Trimethyl-Indoleninium-5-Sulfonate is also employed in the agrochemical industry for the synthesis of new pesticides and other crop protection agents. Its incorporation into these compounds can lead to enhanced performance and selectivity, ultimately contributing to more effective and environmentally friendly agricultural practices.
Used in Dye and Pigment Industry:
In the dye and pigment industry, 1-Ethyl-2,3,3-Trimethyl-Indoleninium-5-Sulfonate is used as a starting material for the production of various dyes and pigments. Its pink solid form and chemical properties make it suitable for creating a wide range of colors and shades, which can be used in various applications such as textiles, plastics, and printing inks.
Used in Research and Development:
1-Ethyl-2,3,3-Trimethyl-Indoleninium-5-Sulfonate is also used in research and development laboratories for the exploration of new chemical reactions and the development of innovative synthetic methods. Its unique properties make it an interesting candidate for studying various aspects of organic chemistry, including reaction mechanisms, stereochemistry, and catalysis.

InChI:InChI=1/C13H17NO3S/c1-5-14-9(2)13(3,4)11-8-10(18(15,16)17)6-7-12(11)14/h6-8H,5H2,1-4H3

Upstream product

• 132557-72-3 2,3,3-trimethylindole-5-sulfonic acid 
• 563-80-4 3-methyl-butan-2-one 
• 98-71-5 4-hydrazino-benzenesulfonic acid 
• 103905-55-1 1-ethyl-2,3,3-trimethyl-3H-indolium tosylate 
• 80-40-0 ethyl ester of p-toluenesulfonic acid 
• 75-03-6 ethyl iodide 

Downstream Products

• 917979-28-3 3H-indolium-2-[(1E,3E,5E)-5-[1-(5-carboxypentyl)-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene]-1,3-pentadienyl]-1-ethyl-3,3-dimethyl-5-sulfo-, inner salt 
• 235749-10-7 3H-indolium-1-(5-carboxypentyl)-2-[(1E,3E)-3-(1-ethyl-1,3-dihydro-3,3-dimethyl-5-sulfo-2H-indol-2-ylidene)-1-propenyl]-3,3-dimethyl-5-sulfo-, inner salt 
• 146368-11-8 1-(5-carboxypentyl)-2-[3,3-dimethyl-5-sulfo-1-(4-sulfobutyl)-2,3-dihydro-1H-indol-2-yliden]-1,3-pentadienyl-3,3-dimethyl-3H-indolium-5-sulfonate 
• 1240125-28-3 C₃₁H₃₈N₂O₈S₂ 
• 1251915-08-8 C₂₂H₂₄N₂O₄S 
• 146397-21-9 C₂₄H₂₆N₂O₄S 
• 1251915-09-9 C₂₆H₂₈N₂O₄S 
• 440670-12-2 sulfoindotricarbocyclohexen-μ-(chloro) cyanine 
• 146368-09-4 C₂₀H₂₂N₂O₃S 
• 917979-28-3 1-(5-carboxypentyl)-2-[(1E,3E)-5-(1-ethyl-3,3-dimethyl-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)-1,3-pentadienyl]-3,3-dimethyl-5-sulfo-3H-indolium 
• 146397-21-9 1-ethyl-3,3-dimethyl-2-((1E,3E)-4-(N-phenylacetamido)buta-1,3-dien-1-yl)-3H-indol-1-ium-5-sulfonate 
• 1251915-08-8 2-{(E)-2-[acetyl(phenyl)amino]vinyl}-1-ethyl-3,3-dimethyl-3H-indolium-5-sulfonate 
• 146368-09-4 (E)-1-ethyl-3,3-dimethyl-2-(2-(phenylamino)vinyl)-3H-indol-1-ium-5-sulfonate 

Relevant academic research and scientific papers

Sulfo - Cy3 carboxylic acid fluorescent dye and preparation process thereof

The invention relates to a sulfo - Cy3 carboxylic acid fluorescent dye and a preparation process thereof, wherein the synthesized sulfo - Cy3 carboxylic acid has fluorescent quantum yield. At the same time, the high-emission high-excitation wavelength and is easily dissolved in water physical and chemical property stability points, and simultaneously, a single condensation target product needs to be selectively generated when the indole α-position methyl activity is achieved through simultaneous construction of the benzylindole two-side branch chains and high in yield, and C18 column separation is avoided.

NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF

The present invention refers to biomolecule marker has a cyanine compound and number to the next formula 1 bath method are disclosed. [Formula 1] Another test, R1 , R2 , R3 , R4 , B, m and n each specification defines efined. (by machine translation)

A near-infrared heptamethine aminocyanine dye with a long-lived excited triplet state for photodynamic therapy

A water-soluble near-infrared aminocyanine dye has been developed with a long triplet-state lifetime (τ = 9.16 μs in deaerated ethanol). Thereby, extremely high singlet oxygen quantum yield (ΦΔ = 0.20) and low dark cytotoxicity (IC50 = 715.4 μM) were achieved. The potential of the dye as a PDT photosensitizer was demonstrated.

Bioorthogonally Applicable Fluorogenic Cyanine-Tetrazines for No-Wash Super-Resolution Imaging

The synthesis, fluorogenic characterization, and labeling application of four tetrazine-quenched cyanine probes with emission maxima in the red-far red range is reported. Fluorescence of the cyanine-cores is quenched via through-bond-energy-transfer (TBET) exerted by a bioorthogonal tetrazine unit. Upon bioorthogonal labeling reaction with cyclooctyne tagged proteins, the quenching effect ceases, and thus the fluorescence reinstates, resulting in an increase in fluorescence intensity. As a rare example among indocyanines, one of our new probes was found suitable in STED-based super-resolution imaging. The applicability of this fluorogenic Tet-Cy3 probe was therefore further demonstrated in the bioorthogonal labeling of cytoskeletal protein, actin, with subsequent super-resolution microscopy (STED) imaging even under no-wash conditions.

Near-infrared aminocyanine dyes with long-life triplet excited state and preparation method of dyes

The invention provides near-infrared aminocyanine dyes with a long-life triplet excited state in the structural formula I. In the formula, X is C(CH3)2, O, S or Se; R1 and R2 are independently selected from C1-C18 alkyl or benzyl, and R3 and R4 are H, SO3R6, CO2R7 or NCS; Y is a halogen ion, ClO4, PF6, BF4, CH3COO or OTs. The heptamethine aminocyanine dye compounds I have longertriplet excited state life and higher singlet state oxygen production capability as compared with commercial dye ICG (indocyanine green) and have the potential as a near-infrared photosensitizer for photodynamic therapy.

NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF

The present invention relates to a novel cyanine compound which is represented by chemical formula 1, and is used for biomolecular labeling. The present invention further relates to a production method thereof. In the chemical formula 1, R_1, R_2, R_3, R_4, B, m, and n are the same as defined in the present specification.COPYRIGHT KIPO 2017

A class of amino cyanine fluorochrome and its preparation method and application

The invention discloses amino cyanine fluorescent dyes connected with cyclopeptide [cyclo(RGD)] and a preparation method therefor and application thereof. The structural formula of the compounds is shown in I. The compounds consist of structural units III and III; the structural unit II is a derived cyanine dye structure which is water soluble fluorescent molecules, the spectrum of which has relatively great Stokes shift, and the molecules have relatively less toxicity to normal cells; the structural unit III is a cyclopeptide structure of a specific ligand of an alpha v beta 3 integrin receptor and can be used for targeted orientation. The fluorescent dyes have the double function characteristic of tumor imaging diagnosis and targeted therapy.

Imaging agents useful for brain and prepration method thereof

The present invention relates to a fluorescent dye for brain imaging, which is represented by the following [Chemical Formula 1]. [Chemical Formula 1] In the [Chemical Formula 1], R_1, R_2, R_3, R_4, R_5, and n are as defined in the specification.(AA) Example 1(BB) Example 3(CC) Example 4(DD) Example 5COPYRIGHT KIPO 2017

FLUORESCENCE COMPOUNDS AND PREPARATION METHOD THEREOF

Provided is a fluorescent compound represented by the following [Chemical Formula 1] and a method for preparing the same: wherein each of X, Y, R1, R2, R3 and n is the same as defined in the specification.

NOVEL CYANINE COMPOUND FOR LABELING BIOMOLECULE AND PREPARATION METHOD THEREOF

The present invention relates to a novel cyanine compound represented by chemical formula 1 for labeling a biomolecule, and to a preparation method thereof. In chemical formula 1, each of R_1, R_2, R_3, R_4, B, m, and n is the same as defined in the specification. The cyanine compound has high stability, and thus can be easily stored for a long period of time. Also, the cyanine compound does not generate byproducts after a biomolecule forms a bond with a pigment, and thus does not require a subsidiary purification process.