1464-69-3

Usage

Uses

Used in Adhesives Industry:
2-(Vinyloxy)ethyl methacrylate is used as a monomer for the production of adhesives, contributing to their improved adhesion and durability. Its chemical properties allow for the creation of strong bonds in various applications.
Used in Paints and Coatings Industry:
In the paints and coatings industry, 2-(Vinyloxy)ethyl methacrylate is utilized as a monomer to formulate coatings with enhanced resistance to chemicals and weathering. This results in longer-lasting and more resilient surfaces.
Used in Sealants Industry:
2-(Vinyloxy)ethyl methacrylate is employed as a monomer in the production of sealants, where it improves the adhesion and durability of the sealant materials, ensuring a longer-lasting and more effective seal.
Safety Considerations:
It is crucial to handle 2-(vinyloxy)ethyl methacrylate with care due to its potential to cause skin and eye irritation. Additionally, it can be harmful if ingested or inhaled, necessitating proper safety measures during its use and storage.

InChI:InChI=1/C8H12O3/c1-4-10-5-6-11-8(9)7(2)3/h4H,1-2,5-6H2,3H3

Upstream product

• 764-48-7 ethyleneglycol vinyl ether 
• 80-62-6 methacrylic acid methyl ester 
• 97-88-1 2-methyl-butyl acrylate 
• 920-46-7 Methacryloyl chloride 

Downstream Products

• 534-15-6 1,1-dimethoxyethane 

Relevant academic research and scientific papers

Fabrication of Acidic pH-Cleavable Polymer for Anticancer Drug Delivery Using a Dual Functional Monomer

The preparation of tumor acidic pH-cleavable polymers generally requires tedious postpolymerization modifications, leading to batch-to-batch variation and scale-up complexity. To develop a facile and universal strategy, we reported in this study design and successful synthesis of a dual functional monomer, a-OEGMA that bridges a methacrylate structure and oligo(ethylene glycol) (OEG) units via an acidic pH-cleavable acetal link. Therefore, a-OEGMA integrates (i) the merits of commercially available oligo(ethylene glycol) monomethyl ether methacrylate (OEGMA) monomer, i.e., hydrophilicity for extracellular stabilization of particulates and a polymerizable methacrylate for adopting controlled living radical polymerization (CLRP), and (ii) an acidic pH-cleavable acetal link for efficiently intracellular destabilization of polymeric carriers. To demonstrate the advantages of a-OEGMA (Mn = 500 g/mol) relative to the commercially available OEGMA (Mn = 300 g/mol) for drug delivery applications, we prepared both acidic pH-cleavable poly(?-caprolactone)21-b-poly(a-OEGMA)11 (PCL21-b-P(a-OEGMA)11) and pH-insensitive analogues of PCL21-b-P(OEGMA)18 with an almost identical molecular weight (MW) of approximately 5.0 kDa for the hydrophilic blocks by a combination of ring-opening polymerization (ROP) of ?-CL and subsequent atom transfer radical polymerization (ATRP) of a-OEGMA or OEGMA. The pH-responsive micelles self-assembled from PCL21-b-P(a-OEGMA)11 showed sufficient salt stability, but efficient acidic pH-triggered aggregation that was confirmed by the DLS and TEM measurements as well as further characterizations of the products after degradation. In vitro drug release study revealed significantly promoted drug release at pH 5.0 relative to the release profile recorded at pH 7.4 due to the loss of colloidal stability and formation of micelle aggregates. The delivery efficacy evaluated by flow cytometry analyses and an in vitro cytotoxicity study in A549 cells further corroborated greater cellular uptake and cytotoxicity of Dox-loaded pH-sensitive micelles of PCL21-b-P(a-OEGMA)11 relative to the pH-insensitive analogues of PCL21-b-P(OEGMA)18. This study therefore presents a facile and robust means toward tumor acidic pH-responsive polymers as well as provides one solution to the trade-off between extracellular stability and intracellular high therapeutic efficacy of drug delivery systems using a novel monomer of a-OEGMA with dual functionalities.

Photoresist resin monomer synthesized from carboxylic acid compound and synthesis method thereof

The invention discloses a photoresist resin monomer synthesized from a carboxylic acid compound and a synthesis method of the photoresist resin monomer, and belongs to the field of chemical synthesisand photoetching materials. The structural general formula of the resin monomer is shown in the specification, wherein R is linear chain or branched chain alkyl. The synthesis method of the resin monomer comprises the following steps: carrying out esterification reaction on a vinyl ether alcohol compound and an acrylic acid compound to obtain an intermediate; and carrying out a reaction on the intermediate and 2, 5-dioxobicyclo[2.2. 2]octane-1, 4-dicarboxylic acid to generate the photoresist resin monomer. The resin monomer provided by the invention comprises an acetal structure and polycyclicand polyester structures, can prevent diffusion of a photoacid generator, improve edge roughness, increase contrast and improve resolution, has excellent etching resistance and fat solubility, and issimple and convenient in preparation method.

Acid-responsive cross-linked polymer prodrug, and preparation method and application thereof

The invention discloses an acid-responsive cross-linked polymer prodrug, and a preparation method and an application thereof. The acid-responsive cross-linked polymer prodrug is prepared through the following main steps: allowing a vinyl alkyl ether acrylate monomer and a derivative thereof to be connected with a hydroxyl-containing chemotherapeutic drug through an acid-responsive acetal bond so as to form a drug-micromolecule compound, and allowing the drug-micromolecule compound to be connected with sulfhydrylated PEG through a Michael addition reaction so as to obtain the acid-responsive cross-linked polymer prodrug. Compared with the prior art, the acid-responsive cross-linked polymer prodrug micelle with high drug loading capacity and high stability is prepared by modification of chemotherapeutic drugs, and has wide application prospects in the anti-tumor aspect.

SALT, ACID GENERATOR, RESIN, RESIST COMPOSITION AND METHOD FOR PRODUCING RESIST PATTERN

A salt represented by formula (I): wherein Q1 and Q2 independently represent a fluorine atom or a C1 to C6 perfluoroalkyl group, R1 and R2 in each occurrence independently represent a hydrogen atom, a fluorine atom or a C1 to C6 perfluoroalkyl group, z represents an integer of 0 to 6, X1 represents *—CO—O—, *—O—CO— or —O—, * represents a binding position to C(R1)(R2) or C(Q1)(Q2), A1 represents a C4 to C24 hydrocarbon group having a C4 to C18 divalent alicyclic hydrocarbon moiety, A2 represents a C2 to C12 divalent hydrocarbon group, R3 and R4 independently represent a hydrogen atom or a C1 to C6 monovalent saturated hydrocarbon group, R5 represents a hydrogen atom, a fluorine atom, or a C1 to C6 alkyl group where a hydrogen atom may be replaced by a fluorine atom, and Z+ represents an organic cation.

COMPOUND, ACID GENERATOR, RESIN, RESIST COMPOSITION AND PRODUCTION METHOD OF RESIST PATTERN

PROBLEM TO BE SOLVED: To provide a compound, a resin to be used for a resist composition, and a resist composition, from which a resist pattern can be produced with excellent line edge roughness. SOLUTION: The present invention discloses a compound represented by formula (I), a resin derived from the compound, an acid generator containing the compound, and a resist composition comprising the resin and the acid generator. In the formula, Q1 and Q2 each represent a fluorine atom or a perfluoroalkyl group; R1 and R2 each represent a hydrogen atom, a fluorine atom or a perfluoroalkyl group; z represents an integer of 0 to 6; X1 represent *-CO-O-, *-O-CO-, or the like; A1 represents a divalent alicyclic hydrocarbon group-containing hydrocarbon group; A2 represents a divalent hydrocarbon group; R3 and R4 each represent a hydrogen atom or a saturated hydrocarbon group; R5 represent an alkyl group which may have a halogen atom, or the like; R6 represents an aromatic hydrocarbon group which may have a substituent; and R7 represents a hydrocarbon group which may have a substituent, a cyano group or the like. SELECTED DRAWING: None COPYRIGHT: (C)2017,JPOandINPIT

Composition of vinyl ether group containing (meth)acrylic acid ester and production method thereof

It is an object of the present invention to provide a vinyl ether group-containing (meth)acrylic ester, which has both radical polymerizability and cation polymerizability, improved in storage stability and stability in handling without impairing its polymerizability or, in other words, provide a stabilized vinyl ether group-containing (meth)acrylic ester. Another object is to provide a method of producing a stabilized vinyl ether group-containing (meth)acrylic ester composition. A further object is to provide a method of stably handing, a method of economically and stably producing and a method of purifying a vinyl ether group-containing (meth)acrylic ester. A vinyl ether group-containing (meth)acrylic ester composition which comprises a radical polymerization inhibitor and a vinyl ether group-containing (meth)acrylic ester represented by the following general formula (1):CH2=CR1-COO-R2-O-CH=CH-R3 in the formula, R1 represents a hydrogen atom or a methyl group, R2 represents an organic residue and R3 represents a hydrogen atom or an organic residue.

VINYLOXYETHYL ESTERS OF MONOCARBOXYLIC ACIDS.

The authors examine methods of synthesis and the properties of 2-vinyloxyethyl acylates, a little-studied class of organic compounds on which literature information is very limited and which are of interest as possible monomers for synthesis of macromolecular compounds and as synthetic models of natural physiologically active substances. Methods have been devised for synthesis of 2-vinyloxyethyl acylates - potential monomers for synthesis of macromolecular and physiologically active compounds. The structural characteristics of the synthesized compounds were studied. Cationic polymerization of 2-vinyloxyethyl acylates was carried out, and the dependence of the reaction rate and of the properties of the resultant oligomers on the nature of the acyl radical was determined.

SYNTHESIS OF VINYL ETHERS AND SULFIDES WITH METHACRYLATE GROUPS

Vinyloxyalkyl methacrylates were obtained by transesterification of methyl methacrylate with the vinyl monoethers of diols.The best catalysts for transesterification are lithium and sodium vinyloxyalkoxides, and the hydroquinone-phenyl-β-naphthylamine system is an inhibitor of polymerization. 2-(Vinylthio)ethyl methacrylate was obtained from 2-vinylthioethanol.