146464-49-5Relevant academic research and scientific papers
Oxadiazoles as ester bioisosteric replacements in compounds related to disoxaril. Antirhinovirus activity
Diana,Volkots,Nitz,Bailey,Long,Vescio,Aldous,Pevear,Dutko
, p. 2421 - 2436 (2007/10/02)
A series of 1,2,4-oxadiazoles has been prepared as ester bioisosteres and tested against 15 human rhinovirus serotypes, and the MIC80, the concentration which inhibits 80% or 12 of the serotypes tested, was determined. Homologation of the alkyl
1,2,4-oxadiazolyl-phenoxyalkylisoxazoles and their use as antiviral agents
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, (2008/06/13)
Compounds of the formula STR1 wherein: Y is alkylene of 3 to 9 carbon atoms; R1 is lower-alkyl, lower-alkoxy-(C1-3 -alkyl), lower-alkoxycarbonyl, cyclopropyl or trifluoromethyl; R2 and R3 independently are hydro
