146547-12-8

Basic information

• Product Name: 1,6-di-O-(tert-butyldiphenyl)silyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol
• CAS NO: 146547-12-8
• Molecular Weight: 667.048
• Mol File: 146547-12-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 1,6-di-O-(tert-butyldiphenyl)silyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-di-O-(tert-butyldiphenyl)silyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol(146547-12-8)
• EPA Substance Registry System: 1,6-di-O-(tert-butyldiphenyl)silyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol(146547-12-8)

Safety Data

• Hazardous Substances Data: 146547-12-8(Hazardous Substances Data)

Upstream product

• 598-53-8 isopropyl methyl ether 
• 146547-11-7 (2S,5S)-1,6-bis[(tert-butyldiphenylsilyl)oxy]hexane-2,5-diol 
• 24211-51-6 (2S,5S)-hexane-1,2,5,6-tetrol 
• 58479-61-1 tert-butylchlorodiphenylsilane 

Downstream Products

• 146547-14-0 1,6-di-O-benzyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol 
• 127221-56-1 1,6-di-O-benzyl-2,5-di-O-tosyl-3,4-dideoxy-D-threo-hexitol 
• 127221-57-2 N-benzyl-trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine 
• 127221-55-0 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol 
• 127221-54-9 trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine 

Relevant articles and documents

Asymmetric hydrogenation of β-keto esters

Enantiomerically pure β-hydroxy esters are prepared by a process in which β-keto esters are reacted with hydrogen in the presence of catalysts of the formula LRuX2where X is halogen, acetate, allyl, methallyl, 2-phenylallyl, perchlorate, trifluoroacetate, tetrafluoroborate, hexafluoroantimonate, hexafluorophosphate, hexafluoroarsenate or trichloroacetate, L is a bidentate phospholane of the formula I ?where B=a bridging link with 1-5 carbon atoms between the two phosphorus atoms, R1=H, C1-C6-alkyl, aryl, alkylaryl or SiR23, R2=alkyl or aryl, m=0 or 1, R3=H or OR4, and R4=R1, with the proviso that if m=1 then R3=H and if m=0 then R3≠ H.