127221-55-0

Basic information

• Product Name: 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol
• Synonyms: 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol
• CAS NO: 127221-55-0
• Molecular Weight: 330.424
• Mol File: 127221-55-0.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol(CAS DataBase Reference)
• NIST Chemistry Reference: 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol(127221-55-0)
• EPA Substance Registry System: 1,6-di-O-benzyl-3,4-dideoxy-D-threo-hexitol(127221-55-0)

Safety Data

• Hazardous Substances Data: 127221-55-0(Hazardous Substances Data)

Upstream product

• 24211-51-6 (2S,5S)-hexane-1,2,5,6-tetrol 
• 100-39-0 benzyl bromide 
• 146547-14-0 1,6-di-O-benzyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol 
• 321659-05-6 11-[4-(4-tert-butoxycarbonyl-1,7-dithia-4,11-diaza-cyclotetradec-11-ylmethyl)-benzoyl]-1,4,8,11tetraaza-cyclotetradecane-1,4,8-tricarboxylic acid tri-tert-butyl ester 
• 109613-59-4 (S)-1-(benzyloxy)but-3-en-2-ol 
• 251459-11-7 3,4-dideoxy-2,5-O-isopropylidene-1,6-di-O-methyl-D-threo-hexitol 
• 1707-77-3 1,2:5,6-di-O-isopropylidene-D-mannitol 
• 127305-27-5 1,2-bis<(4S)-2,2-dimethyl-1,3-dioxolan-4-yl>ethane 
• 31843-48-8 trans-3,4-Didehydro-3,4-dideoxy-1,2:5,6-di-O-isopropyliden-D-threo-hexitol 
• 3268-36-8 1,2:5,6-di-O-isopropylidene-3,4-O-thioxocarbonyl-D-mannitol 
• 146547-12-8 1,6-di-O-(tert-butyldiphenyl)silyl-2,5-di-O-isopropylidene-3,4-dideoxy-D-threo-hexitol 
• 146547-11-7 (2S,5S)-1,6-bis[(tert-butyldiphenylsilyl)oxy]hexane-2,5-diol 
• 146547-13-9 1,6-di-O-isopropylidene-1,6-di-O-methyl-3,4-dideoxy-D-threo-hexitol 
• 2930-05-4 (S)-benzyl glycidyl ether 

Downstream Products

• 127221-57-2 N-benzyl-trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine 
• 127221-54-9 trans-(2R,5R)-bis(benzyloxymethyl)-pyrrolidine 
• 321917-88-8 4-[(2R,5R)-2,5-bis(benzyloxymethyl)pyrrolidino]pyridine 
• 251459-19-5 1,2-bis[(2R,5R)-2,5-benzyloxymethylphospholanyl]ethane 
• 251441-73-3 (4S,7S)-4,7-Bis(benzyloxymethyl)-2,2-dioxo[1,3,2]dioxathiepane 
• 127221-56-1 1,6-di-O-benzyl-2,5-di-O-tosyl-3,4-dideoxy-D-threo-hexitol 
• 145028-21-3 (2S,5S)-1,6-bis(benzyloxy)-2,5-bis(methylsulfonyloxy)hexane 

Relevant articles and documents

Synthesis of the first water-soluble chiral tetrahydroxy diphosphine Rh(I) catalyst for enantioselective hydrogenation

The synthesis of the first chiral polyhydroxy diphosphine-Rh(I) catalyst for asymmetric hydrogenation is described. Based on a simple synthetic pathway starting from D-mannitol the new metal complex is constructed. A special feature of the approach is the protection of the air-sensitive phosphinegroups by the catalytically active metal in the final synthetic steps. Therefore, tedious P-protection-deprotection procedures could be advantageously avoided. The new water-soluble catalyst hydrogenates functionalized olefins by up to 99.6% ee in water as solvent.

Production of optically active phospholanes

Phospolanes and diphospholanes of the general formula I where: is H, C1-C6-aryl, alkylaryl, SiR32, R2is alkyl or aryl, A is H, C1-C6-alkyl, aryl, Cl or B is a linker with 1-5 C a

Synthesis of C2-symmetric analogues of 4-(pyrrolidino)pyridine: New chiral nucleophilic catalysts

The syntheses of a series of enantiomerically pure C2-symmetric 4-(pyrrolidino)pyridine (PP Y) derivatives by SNAr of 4-halo-/4-phenoxypyridines and by cyclocondensation from 4-aminopyridine are described. Preliminary results pertaining to their use as catalysts for acylative kinetic resolution of 1-phenylethanol are also presented. A single-crystal X-ray analysis of PPY If is reported. The Royal Society of Chemistry 2000.