146566-82-7

Basic information

• Product Name: 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, cis- (9CI)
• Synonyms: 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, cis- (9CI)
• CAS NO: 146566-82-7
• Molecular Formula: C₇H₁₀O₄
• Molecular Weight: 158.1519
• Product Categories: ALDEHYDE
• Mol File: 146566-82-7.mol
• Article Data: 17

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, cis- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, cis- (9CI)(146566-82-7)
• EPA Substance Registry System: 1,3-Dioxolane-4,5-dicarboxaldehyde, 2,2-dimethyl-, cis- (9CI)(146566-82-7)

Safety Data

• Hazardous Substances Data: 146566-82-7(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Usage

Building block in the synthesis of pharmaceuticals and other organic compounds

Reactivity

Versatile, can undergo various chemical reactions to produce a wide range of products

Health hazards

Potential skin and eye irritation

Safety concerns

May be harmful if ingested or inhaled

Precaution

Handle with appropriate safety measures

Upstream product

• 73346-74-4 (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol 
• 37031-29-1 (+)-dimethyl-2,3-O-isopropylidene-D-tartrate 
• 50-70-4 D-sorbitol 
• 67-64-1 acetone 
• 77-76-9 2,2-dimethoxy-propane 
• 38145-93-6 (S)-1-((4R,4'R,5R)-2,2,2',2'-tetramethyl-4,4'-bi(1,3-dioxolan)-5-yl)ethane-1,2-diol 
• 38145-93-6 2,3,4,5-di-O-isopropylidene D-glucitol 
• 3969-59-3 mannitol triacetonide 
• 73346-73-3 (4S,5S)-diethyl 2,2-dimethyl-1,3-dioxolane-4,5-dicarboxylate 
• 3969-84-4 3,4-di-O-isopropylidene-D-mannitol 
• 69-65-8 mannitol 
• 3969-84-4 3,4-O-isopropylidene-D-mannitol 
• 94925-98-1 3,4-O-methylethylidene-D-mannitol 
• 33493-69-5 (1R,1'R)-1,1'-[(4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-diyl]diethane-1,2-diol 

Downstream Products

• 73346-74-4 (4R,5R)-2,2-dimethyl-1,3-dioxolane-4,5-dimethanol 
• 1217890-90-8 (4R,5R)-4,5-diethynyl-2,2-dimethyl-[1,3]dioxolane 
• 152139-64-5 (meso)-3,4-isopropylidenedioxy-2,5-pyrrolidine hydrotosylate 
• 151948-15-1 (3aR,6aS)-5-benzyl-2,2-dimethyltetrahydro-3aH-[1,3]dioxolo[4,5-c]pyrrole 

Relevant articles and documents

A C2-symmetric pool based flexible strategy: An enantioconvergent synthesis of (+)-valiolamine and (+)-valienamine

A new enantioconvergent strategy directed toward the synthesis of glucosidase inhibitors was developed by using a C2-symmetric element within the chiral pool and by applying an iodine-promoted cyclization of an unsaturated carbonimidothioate for the regio- and diastereocontrolled installation of amino and hydroxy units. Not only does this simple flexible strategy provide a convergent concise approach to (+)-valiolamine (1), but it can also be readily adopted for the synthesis of (+)-valienamine (2). Commercially available and cheap C2-symmetric D-tartaric acid served as the chiral building block. Copyright

An improved two-step synthetic route to primary allylic alcohols from aldehydes

An improved two-step synthetic route to allylic alcohols from aldehydes has been developed. A modification of the HWE reaction in H2O-2-PrOH (1 : 1) and a convenient protocol to prepare AlH3 in THF from LiAlH 4 and n-BuBr are the key factors in the improvement.

Concise synthesis of iminocyclitols via petasis-type aminocyclization

(Chemical Equation Presented) A two-step method has been developed to synthesize several biologically important iminocyclitols in ca. 44-60percent yields by using Petasis-type condensation. The method is very generaland operationally simple, affording a s