14674-22-7

Upstream product

• 38622-91-2 [(p-methylphenyl)sulfonylmethyl]isonitrile 
• 331942-49-5 C₇H₆O₂*C₈H₁₉N 
• 10564-55-3 1-isocyanatomethanesulfonyl-4-methyl-benzene 
• 50-00-0 formaldehyd 
• 55-21-0 benzamide 
• 824-79-3 sodium 4-methylbenzenesulfinate 
• 38792-42-6 N-(chloromethyl)benzamide 
• 39538-86-8 silver p-toluenesulfonate 
• 536-57-2 p-toluene sulfinic acid 
• 38221-33-9 N-<(diethylamino)methyl>benzamide 

Downstream Products

• 103635-47-8 C₉H₁₁N₃O₃ 
• 103635-48-9 C₁₀H₁₃N₃O₃ 
• 40734-92-7 N-(tosylmethyl)thiobenzamide 
• 127722-21-8 N?{[(4?methylphenyl)sulfonyl]methyl}benzenecarboximidoyl chloride 
• 372200-06-1 N-(2-oxo-2-[4]pyridyl-ethyl)-benzamide 
• 127722-22-9 N'''?{[(4?methylphenyl)sulfonyl]methyl}benzenecarboximidoyl isothiocyanate 
• 127722-26-3 5-Phenyl-1-(toluene-4-sulfonylmethyl)-1H-tetrazole 
• 127722-32-1 2,5-Diphenyl-4-(toluene-4-sulfonyl)-oxazole 
• 127722-28-5 2-Phenyl-3-(toluene-4-sulfonylmethyl)-3H-quinazolin-4-one 
• 127722-24-1 1-Phenyl-3-{phenyl-[(Z)-toluene-4-sulfonylmethylimino]-methyl}-thiourea 
• 58443-28-0 (2,4-diphenyl-1H-pyrrol-3-yl)(phenyl)methanone 
• 59009-65-3 methyl N-(tosylmethyl)thiobenzimidate 
• 59009-61-9 methyl 2,4-diphenylpyrrole-3-carboxylate 
• 59009-62-0 2,4-diphenyl-1H-pyrrole-3-carbonitrile 

Relevant academic research and scientific papers

Design of new imidazole derivatives with anti-HCMV activity: QSAR modeling, synthesis and biological testing

The problem of designing new antiviral drugs against Human Cytomegalovirus (HCMV) was addressed using the Online Chemical Modeling Environment (OCHEM). Data on compound antiviral activity to human organisms were collected from the literature and uploaded

Mild oxidation of tosylmethylisocyanide to tosylmethylisocyanate: Utility in synthetic and medicinal chemistry

A convenient and efficient (one-step) oxidation is reported of commercially available tosylmethylisocyanide (TOSMIC) to form tosylmethylisocyanate, making this highly reactive bifunctional molecule a readily available synthetic reagent. Besides engaging in nucleophilic addition reactions with alcohols, amines, and thiols, tosylmethylisocyanate also reacts with carboxylic acids to form tosylmethylamides, which undergo substitution reactions in the presence of organocopper and organomagnesium reagents.

N-(ARYLSULFONYLMETHYL)BENZIMIDOYL CHLORIDES - ACCESSIBLE REAGENTS FOR HETEROCYCLIZATIONS

The action of phosphorus pentachloride on the products from the condensation of N-(chloromethyl)benzamide with sodium benzene- or p-toluenesulfinate gave the corresponding N-(arylsulfonylmethyl)benzimidoyl chlorides.The products are suitable for heterocyc