146764-48-9Relevant academic research and scientific papers
A novel reagent for regioselective cleavage of 2,3-epoxyalcohols by fluoride - A synthesis of 3-fluoro-293-dideoxy-d-erythro-pentose
Nikitenko, Antonia A.,Arshava, Boris M.,Mikerin, Igor E.,Raifeld, Yuri E.,Lee, Ving J.,Lang Jr., Stanley A.
, p. 7087 - 7088 (1992)
The cleavage of the oxirane ring of 3,4-anhydro-2deoxy-D-threo-pentose diethyl acetal by (isopropoxy)-titanium fluorides is discussed. The high regioselectivity found with bis(isopropoxy) titanium difluoride is the basis for an enantioselective synthesis of 3-fluoro-2,3-deoxy-D-erythreo-pentose from a non-carbohydrate precursor.
