1468-55-9Relevant academic research and scientific papers
Process for preparing α-chloro-ε-caprolactam
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, (2008/06/13)
A process is described for preparing α-chloro-ε-caprolactam, an intermediate for the synthesis of L-lysine, comprising reacting an N-substituted -α-chloro-ε-caprolactam, wherein the N-substituent is an organic radical selected from the group consisting of arylsulfonyl, aroyl and alkanoyl radicals, with ε-caprolactam at a temperature within the range of about 50° to about 250° C to form α-chloro-ε-caprolactam and an N-substituted-ε-caprolactam. A continuous process is also described for the production of α-chloro-ε-caprolactam further comprising the chlorination of N-substituted-ε-caprolactam to produce N-substituted-α-chloro-ε-caprolactam.
